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Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)
Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)

An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their...

Common LISP. The Language. Second Edition
Common LISP. The Language. Second Edition

The defacto standard - a must-have for all LISP programmers.

In this greatly expanded edition of the defacto standard, you'll learn about the nearly 200 changes already made since original publication - and find out about gray areas likely to be revised later. Written by the Vice- Chairman of X3J13 (the ANSI
...

Extracellular Nucleotides and Nucleosides: Release, Receptors, and Physiological & Pathophysiological Effects, Volume 54 (Current Topics in Membranes)
Extracellular Nucleotides and Nucleosides: Release, Receptors, and Physiological & Pathophysiological Effects, Volume 54 (Current Topics in Membranes)

Purinergic receptors are proteins that bind ATP as their extracellular ligand. Once thought only as an intracellular molecule that provides energy, ATP is also now considered an essential autocrine/paracrine agonist that acts extracellularly within tissues and tissue microenvironments. Receptors for ATP and its metabolites, so-called...

Roitt's Essential Immunology, Tenth Edition (Essentials)
Roitt's Essential Immunology, Tenth Edition (Essentials)

Roitt's Essential Immunology has established itself as the book of choice for students of immunology worldwide. This excellent textbook is commonly regarded as 'the best of the immunology primers' and the tenth edition remains at the cutting edge of this fascinating area of science.

The trademark of this book is...

G Protein Signaling: Methods and Protocols (Methods in Molecular Biology)
G Protein Signaling: Methods and Protocols (Methods in Molecular Biology)

A collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. Among the readily reproducible techniques presented are those for the purification of G proteins and effectors enzymes, assays of these purified G proteins and effector enzymes,...

Root Genomics and Soil Interactions
Root Genomics and Soil Interactions

Fully integrated and comprehensive in its coverage, Root Genomics and Soil Interactions examines the use of genome-based technologies to understand root development and adaptability to biotic and abiotic stresses and changes in the soil environment. Written by an international team of experts in the field, this timely review highlights...

Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)
Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)

12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are,...

Introduction to Mobile Telephone Systems: 1G, 2G, 2.5G, and 3G Technologies and Services
Introduction to Mobile Telephone Systems: 1G, 2G, 2.5G, and 3G Technologies and Services

If you are involved or getting involved in mobile communication technologies and services, this book is for you. This book explains the different types of mobile telephone technologies and systems from 1st generation digital broadband. It describes the basics of how they operate, the different types of wireless voice, data and information...

Carrier Grade Voice Over IP (second edition)
Carrier Grade Voice Over IP (second edition)
NEW EDITION OF---CUTTING-EDGE SOLUTIONS CUT-TO-THE-CHASE STYLE

In the race to put carrier-quality voice over IP (VoIP)——those using this book run faster and falter less. International expert Daniel Collins’ greatly enhanced Carrier Grade Voice over IP brings you leading-edge signaling schemes,...

Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)
Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this...

Fungal Pathogenesis: Principles and Clinical Applications (Mycology)
Fungal Pathogenesis: Principles and Clinical Applications (Mycology)

Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens!

This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular
...

Breast Cancer: Translational Therapeutic Strategies (Translational Medicine)
Breast Cancer: Translational Therapeutic Strategies (Translational Medicine)

Considering the impact of translational breakthroughs on the early detection, diagnosis, prevention, and treatment of breast cancer, this all-encompassing guide collects cutting-edge research on the most promising strategies and agents likely to impact the management and long-term outcomes of women with breast cancer. This book will provide...

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