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Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)
Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)

12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are,...

Interferon Methods and Protocols (Methods in Molecular Medicine)
Interferon Methods and Protocols (Methods in Molecular Medicine)

A compendium of optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. These cutting-edge techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon. The protocols follow the successful...

Apoptosis, Senescence and Cancer (Cancer Drug Discovery and Development)
Apoptosis, Senescence and Cancer (Cancer Drug Discovery and Development)
The goals of chemotherapy (and radiotherapy) are to eliminate tumor cell targets by promoting cell death. In recent years, a major focus has been placed on programmed cell death or apoptosis as the primary mechanism of cell killing. However, tumor cells may respond to various forms of treatment in diverse ways, only some of which...
Cardiovascular Proteomics: Methods and Protocols (Methods in Molecular Biology)
Cardiovascular Proteomics: Methods and Protocols (Methods in Molecular Biology)
Over the past few years, the power and potential of proteomics has become widely recognized. The use of proteomics for the study of complex diseases is increasing and is particularly applicable to cardiovascular disease, the leading cause of death in developed countries. The ability to investigate the complete proteome provides a...
Bone Resorption (Topics in Bone Biology)
Bone Resorption (Topics in Bone Biology)
Bone Resorption, the second volume of the series Topics in Bone Biology, is centered on the osteoclast, the bone-resorbing cell. The volume thus complements the first volume of the series, Bone Formation, which discussed origin, function, and pathology of the bone-forming cell, the osteoblast.Both volumes are addressed to...
Color Atlas of Genetics, Third Edition (Flexibook)
Color Atlas of Genetics, Third Edition (Flexibook)

A remarkable achievement by a single author ... concise but informative ... No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition. --American Journal of Medical Genetics

More than ever, a solid understanding of genetics is a fundamental element of all medical...

Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases (Ernst Schering Foundation Symposium Proceedings)
Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases (Ernst Schering Foundation Symposium Proceedings)

Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g,...

Protein Tyrosine Phosphatase Control of Metabolism
Protein Tyrosine Phosphatase Control of Metabolism

Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic cellular processes. Among these important roles is the regulation of cellular...

Fungal Pathogenesis: Principles and Clinical Applications (Mycology)
Fungal Pathogenesis: Principles and Clinical Applications (Mycology)

Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens!

This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular
...

High Speed Digital Design: Design of High Speed Interconnects and Signaling
High Speed Digital Design: Design of High Speed Interconnects and Signaling

High Speed Digital Design discusses the major factors to consider in designing a high speed digital system and how design concepts affect the functionality of the system as a whole. It will help you understand why signals act so differently on a high speed digital system, identify the various problems that may occur in the design, and...

Biocommunication of Animals
Biocommunication of Animals

Every coordination within or between animals depends on communication processes. Although the signaling molecules, vocal and tactile signs, gestures and its combinations differ throughout all species according their evolutionary origins and variety of adaptation processes, certain levels of biocommunication can be found in all animal...

Calcium Signalling in Cancer
Calcium Signalling in Cancer

Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an...

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