This topical volume provides an overview of clinically relevant data on anticancer agents. It is not only intended medical doctors working with cancer patients, and for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics. Apart from new targets for...
'Ototoxicity' is a compendium of information on the ototoxic potential of clinically useful drugs. Each section of this thorough text is written by a leading authority in the field. The book reviews the important classes of medications known to cause ototoxicity and their mechanisms. Clinical manifestations, what is known about...
In recent years the development of new technologies has permitted the production of 'functional' or 'smart' textiles. These fabrics are capable of sensing changes in environmental conditions or body functions and are adequately responding to them. They are able to absorb substances from the skin or to release therapeutic or...
From the emergence of clinical sleep medicine marked by the establishment of the harbinger Stanford Sleep Disorders Clinic in the mid 1970s, offspring sleep dis- ders clinics and centers have grown exponentially with the recognition of the unmet diagnostic and treatment needs of the reservoir of patients suffering from sy- toms of what are...
This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance...
It is well-known that the daily diet plays an important role in the preservation and integrity of renal function in patients with chronic kidney disease. However, there currently exists some confusion as to the right diet because of the MDRD (Modification of Diet in Renal Disease) study, which has shown that a low-protein diet does not have a...
Dental Erosion: A challenge for the 21st century! This monograph offers a
guide towards better oral health in the future. Erosive tooth wear is a multifactorial
condition of growing concern to the clinician and the subject of extensive
research – a view supported by the literature and impressions from many international...
Over the next decade, the global number of people with diabetes and at risk of diabetes and cardiovascular disease is expected to grow by 25%, largely driven by the rising prevalence of obesity and inactivity. The problem is especially serious in Asia, where the WHO predicts that in less than a decade, 60% of the worldwide population with...
This book unfolds the history of the discovery of the transmembrane channel which is responsible for the ‘funny’ or If current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina pectoris....
A quick reference guide to the diagnosis and treatment of common primary care problems. The information is presented in such a way as to help students and physicians quickly form a list of possible diagnoses, perform a cost-effective diagnostic work-up, and prescribe therapy for the most common causes of acute and chronic complaints....
This book is a derivative of the author’s well-regarded Cerebral Palsy and focuses on rehabilitation techniques. The book discusses the theory and techniques used by physical and occupational therapists, and also provides suggestions for implementing an Individual Education Plan. The book includes chapters on rehabilitation techniques....
In the care of pediatric patients, infectious diseases comprise over 50% of the clinical diagnoses. For this reason, it is essential to have a basic understanding of infectious processes and to keep abreast of new developments in the field. This reference stands as a convenient and time-saving reference for clinicians on the diagnosis,...
