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Hematopoietic Growth Factors in Oncology: Basic Science and Clinical Therapeutics (Cancer Drug Discovery and Development)

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Leading oncologists, hematologists, and nephrologists comprehensively review the role of HGFs in clinical practice, explain the molecular basis of their effects, and consider potential future developments. The authors focus on the use of HGFs in oncology, describing their cutting-edge application to patients with lung cancer, Hodgkin's and nonhodgkin's lymphoma, breast cancer, chronic lymphocytic leukemia, AIDS-related malignancies, myelodysplastic syndromes, and aplastic anemias. Among the HGFs described are granulocyte colony-stimulating factor, erythropoietc factors, thrombopoietic factors, and stem cell factor and its receptor, C-kit. To complete their survey, the contributors also consider the safety and economic implications of HGFs and the future potential for HGF antagonists in oncology.

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C# 5 First Look
C# 5 First Look

C# is a wonderfully expressive and powerful language that lets you focus on your application rather than low level boilerplate. Over the last decade, the C# compiler has evolved to include many features from dynamic and functional languages, all while remaining statically typed. Most recently, it also tackles the proliferation of concurrent...

Z-80 Microprocessor: Architecture, Interfacing, Programming and Design
Z-80 Microprocessor: Architecture, Interfacing, Programming and Design

This text is intended for microprocessor courses at the undergraduate level in technology and engineering. ll is a comprehensive treatment of the microprocessor. covering both hardware and software based on the Z80 microprocessor family. The text assumes a course in digital logic as a prerequisite; however, it does not assume a background in...

Molecular Diagnosis of Cancer: Methods and Protocols (Methods in Molecular Medicine)
Molecular Diagnosis of Cancer: Methods and Protocols (Methods in Molecular Medicine)

We are currently experiencing a fundamental shift in the way in which we approach the characterization of cancer. Never before has the make up of cancer tissues and individual cells been so exhaustively researched and char- terized. We are now capable of producing molecular “fingerprints” that ch- acterize the expression of all...


Innovation in Cultural Systems: Contributions from Evolutionary Anthropology (Vienna Series in Theoretical Biology)
Innovation in Cultural Systems: Contributions from Evolutionary Anthropology (Vienna Series in Theoretical Biology)

In recent years an interest in applying the principles of evolution to the study of culture emerged in the social sciences. Archaeologists and anthropologists reconsidered the role of innovation in particular, and have moved toward characterizing innovation in cultural systems not only as a product but also as an evolutionary process. This...

Standards Battles in Open Source Software: The Case of Firefox
Standards Battles in Open Source Software: The Case of Firefox

The browser war between Firefox and Internet Explorer presents an intriguing case: how did Firefox manage to achieve a relatively significant market share in a ‘winner-takes-all’ industry? Why did  Firefox manage to gain some market share while other competitors have failed? Is this because of the Open Source characteristics...

The Manager's Guide to Rewards: What You Need to Know to Get the Best For-and From-your Employees
The Manager's Guide to Rewards: What You Need to Know to Get the Best For-and From-your Employees
A manager who understands the ins and outs of his company's compensation system is more likely to be able to retain his best people, keep them motivated, and ensure that they continue to produce outstanding results. Written by compensation experts at the Hay Group--one of the most respected consulting firms in the world--The Manager's Guide to...
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