Chiral amines are powerful pharmacophores for defining new pharmaceutical drugs (Figure P.1) due to their high density of structural information and inherent ability for hydrogen bonding, yet their synthesis remains a challenge. That challenge is further appreciated when framed in the context of the following goal: the introduction of...
Teaching children to ‘think’ has now become an acceptable part of educational practice and the benefits of using activities to develop thinking skills are well researched. It is not, however, always possible to fit this into an already congested timetable and, along with drama and other creative subjects, it is often an occasional...
Healthcare, a vital industry that touches most of us in our lives, faces major challenges in demographics, technology, and finance. Longer life expectancy and an aging population, technological advancements that keep people younger and healthier, and financial issues are a constant strain on healthcare organizations resources and management....
Since its inception in 1876, the telephone has captured the imagination of people around the world. From its simple origins, the telephone has evolved from the humble device it once was to the modern cell phone or satellite phone. The telephone has fundamentally and instantaneously changed the human race’s ability to communicate over...
There is no question that the Web has become an integral part of modern life for people around the world, connecting us to each other and to seemingly infinite portals of information in real time. In the era of Web 2.0, barriers to participation have been lowered further and further, and we’ve seen the birth of myriad new people to...
Today DBAs are expected to deploy and manage large databases with quality service and little to no downtime. The DBA's main focus is on increasing productivity and eliminating idle redundancy throughout the enterprise. However, there is no magic set of best practices or hard and fast rules that DBAs need to follow, and this can make life...
Nanostructured materials is one of the hottest and fastest growing areas in today's materials science field, along with the related field of solid state physics. Nanostructured materials and their based technologies have opened up exciting new possibilites for future applications in a number of areas including aerospace, automotive, x-ray...
Until now, most of the advances in robotics have taken place in structured environments. Scientists and engineers have designed highly sophisticated robots, but most are still only able to operate and move in predetermined, planned environments designed specifically for the robots and...
An organisation’s competitive advantage lies in the knowledge of its employees and the organisation’s ability to harness that knowledge to meet business objectives. Knowledge management is recognised in the construction industry as a potential tool for providing organisational benefits, but for a number of reasons –...
Multimedia data are used more and more widely in human being's life, e.g., videoconferencing, visual telephone, IPTV, etc. Nearly most of the applications need multimedia transmission techniques that send multimedia data from one side to another side and keep the properties of efficiency, robustness and security. Here, the efficiency...
Product management is challenging, complex, and often misunderstood. Across the high-tech industry, drastically different duties and responsibilities are attributed to product management professionals. Diverse interpretations regarding the role of product management have only further confused practitioners and stifled the ability to...
If you knew you couldn't fail, what is the greatest thing you would dare to dream? Is the job you now have the one you've always wanted? Do you work with the kind of people you'd like to work with? As personal success expert Brian Tracy can attest, it's not until you deal with the dissatisfactions of the present that you can...
