Recent advances in mass spectrometry (MS) have pushed the frontiers of analytical chemistry into the biophysical laboratory. As a result, the biophysical community's acceptance of MS-based methods, used to study protein higher-order structure and dynamics,...

This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description...

This book will also be useful to readers who...

Surfaces are a central to geographical analysis. Their generation and manipulation are a key component of geographical information systems (GISs). However, geographical surface data is often not precise. When surfaces are used to model geographical entities, the data inherently contains uncertainty in terms of both position and attribute....

Machine learning, at its core, is concerned...

This book is meant for research scholars, scientists and practitioners involved with the application of computer-based systems in critical applications. Ensuring dependability of systems used in critical applications is important due to the impact of their failures on human life, investment and environment. The individual aspects of...