Within contemporary society, globalization has emerged as a key concern at the centre of ethical, legal and policy debates relating to health care. Conflicts between public interests and individual rights, the challenge of regulating health professionals and access to health services, and the effects of a global market all feature prominently...

Transcranial magnetic stimulation (TMS) was introduced in the mid 1980s in clinical neurophysiology to study the central motor pathways. Research has been exponentially increased since, and many different methods for brain stimulation have been considered during the last decade. This publication focuses on transcranially applied, non- or...

This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future...

"In a clear, engaging style, Dr. Walters tells the tale of each disease like a detective story. He allows each mystery to unfold as it did in reality, often slowly, through the lives of the plants and animals involved, the first human victims, the government officials who tried to respond, and the scientists who ultimately explained what...

Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory...

This book is an update of the previous volume on Mediterranean diets published in 2000, which provided extensive reviews of the various diets existing in the Mediterranean region. Since then, a number of studies have been published on the relationship between a Mediterranean-type of diet and chronic diseases. However, because the ‘diet...

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and...

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They...

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They...

Reports on the latest advances in the field, for new and experienced scientists. Coverage includes the role of T-cells in multiple sclerosis (MS), T-cell autoimmunity and EAE in nonhuman primates, MBP-reactive T-cells in MS, and genetic engineering of brain-specific T-cells for treatment of diseases in the central nervous system. Also...