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Advances in Spinal Fusion: Molecular Science, BioMechanics, and Clinical Management
Advances in Spinal Fusion: Molecular Science, BioMechanics, and Clinical Management
Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds...
Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats
Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats
Promising drug discovery efforts in the race to cure emerging diseases and thwart bioterrorism

It was not too long ago that scientists believed that the discovery of powerful antimicrobial agents and vaccines would lead to the eradication of viral diseases. A warning, however, of the looming threat of viral diseases on U.S. national security...

The Poison Paradox: Chemicals As Friends and Foes
The Poison Paradox: Chemicals As Friends and Foes
To appreciate the dangers and the risks from chemicals of all kinds it is necessary to understand how, when and why they are toxic. This falls within the field of toxicology and is what this book is all about.

I was encouraged to write the book by Dr John Emsley, who is well known for his popular science books on
...
Gene Therapy of Cancer, Second Edition: Translational Approaches from Preclinical Studies to Clinical Implementation
Gene Therapy of Cancer, Second Edition: Translational Approaches from Preclinical Studies to Clinical Implementation

The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful...

Antigen Presenting Cells: From Mechanisms to Drug Development
Antigen Presenting Cells: From Mechanisms to Drug Development

This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system.

...
Protein Tyrosine Phosphatase Control of Metabolism
Protein Tyrosine Phosphatase Control of Metabolism

Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic cellular processes. Among these important roles is the regulation of cellular...

Drugs Affecting Growth of Tumours (Milestones in Drug Therapy)
Drugs Affecting Growth of Tumours (Milestones in Drug Therapy)

This topical volume provides an overview of clinically relevant data on anticancer agents. It is not only intended medical doctors working with cancer patients, and for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics. Apart from new targets for...

Nanoparticulate Drug Delivery Systems (Drugs and the Pharmaceutical Sciences)
Nanoparticulate Drug Delivery Systems (Drugs and the Pharmaceutical Sciences)
This is an up-to-date text which should find its rightful place on the shelves of postgraduates and more senior scientists in the field. It would be of special value to those in other disciplines who have seen the possibilities of nanomedicine but who have not always appreciated the depth of knowledge that already exists, or the complexity of...
Chemogenomics in Drug Discovery: A Medicinal Chemistry Perspective, Volume 22 (Methods and Principles in Medicinal Chemistry)
Chemogenomics in Drug Discovery: A Medicinal Chemistry Perspective, Volume 22 (Methods and Principles in Medicinal Chemistry)

Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. The first reference devoted to the topic, this up-to-date resource covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the...

Digital People: From Bionic Humans to Androids
Digital People: From Bionic Humans to Androids
Robots, androids, and bionic people pervade popular culture, from classics like Frankenstein and R.U.R. to modern tales such as The Six Million Dollar Man, The Terminator, and A.I. Our fascination is obvious – and the technology is quickly moving from books and films to real life.

In a lab at MIT, scientists and technicians have created...

Natural Products and Cancer Drug Discovery (Cancer Drug Discovery and Development)
Natural Products and Cancer Drug Discovery (Cancer Drug Discovery and Development)

This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools...

Deep in the Shadows: Undercover in the Ruthless World of Human Smuggling
Deep in the Shadows: Undercover in the Ruthless World of Human Smuggling

"You have a lot of enemies, Hipolito. I heard rumors in jail that some of the people you busted are going to try to kill you, so you better watch yourself." U.S. Special Agent Hipolito Acosta had put lots of thugs in jail, but the death threat from an imprisoned convict was still a shock.


Acosta recounts
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