Whether the pursuit is commercially motivated or purely academic, engineering a novel biological catalyst is an enticing challenge. High-resolution protein structure analysis allows for rational alteration of enzyme function, yet many useful enzyme variants are the product of well-designed selection schemes or screening strategies. Enzyme...

Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the...

Reason in Action collects John Finnis' work on the theory of practical reason and moral philosophy. The essays in the volume range from foundational issues of meta-ethics to the practical application of natural law theory to ethical problems such as nuclear deterrence, obscenity and free speech, and abortion and cloning.
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Frankenstein, The Time Machine, Star Trek, Dune, 1984, Blade Runner--science fiction has been explained as a combination of romance, science, and prophecy; as a genre based on an imagined alternative to the reader's environment; and as a form of fantastic fiction and historical literature. It has also been argued that science...

This book documents and evaluates the growing consumer revolution against digital copyright law, and makes a unique theoretical contribution to the debate surrounding this issue. With a focus on recent US copyright law, the book charts the consumer rebellion against the Sonny Bono Copyright Term Extension Act 1998 (US) and the Digital...

This book uniquely integrates a large body of historical, philosophical, psychological, and business models and methods as they relate to executive coaching and leadership development, for individuals, dyads, teams, and executive groups. What is executive wisdom, and how can it be developed through coaching? Executive wisdom emerges from a...

Economics is global and the Eighth Edition of MACROECONOMICS maintains the hallmarks of the Boyes/Melvin series--accessible writing, strong pedagogy, and integration of global economic issues--while faithfully presenting the latest thinking of economists on important macroeconomic phenomena. The authors have carefully integrated their popular...

The relationship between men and the domestic in eighteenth-century Britain has been obscured by two well-established historiographical narratives. The first charts changes in domestic patriarchy, founded on political patriarchalism in the early modern period and transformed during the eighteenth century by new types of family relationship...

How did today's rich states first establish modern fiscal systems? To answer this question, Political Transformations and Public Finances by Mark Dincecco examines the evolution of political regimes and public finances in Europe over the long term. The book argues that the emergence of efficient fiscal institutions was the result of two...

Based on the findings of an extensive research project that surveyed more than 5,500 enterprise employees and functional decision makers across the United States and China, Transforming Business: Big Data, Mobility and Globalization explores the influence...

Energy and environmental issues have caused a marked increase in electricity production from renewable energy sources since the beginning of the 21st Century. The concept of sustainable development and concern for future generations challenge us every day to produce new technologies for energy production, and new patterns of use for these...