Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the...

The book covers...

In Flower Development: Methods and Protocols, researchers in the field detail protocols for  experimental approaches that are currently used to study the formation of flowers, from genetic methods and phenotypic analyses, to genome-wide experiments, modeling, and system-wide approaches. Written in the highly successful Methods...

The pioneering findings of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. Discussion ranges from introductory background on taxonomy, cell structure and physiology, to enzymes and their applications. Alkaliphiles are a relatively recent field of research that will...

Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl-...

This book collects several contributions, written both by statisticians and medical doctors, which focus on the identification of new diagnostic, therapeutic and organizational strategies in order to improve the occurrence of clinical outcomes for Acute Coronary Syndromes (ACS) patients. The work is structured in two different...

Joe Celko's Complete Guide to NoSQL provides a complete overview of non-relational technologies so that you can become more nimble to meet the needs of your organization. As data continues to explode and grow more complex, SQL is becoming less useful for querying data and extracting meaning. In this new world of bigger and faster...

This book provides information on the acquired and genetic basis of aortic diseases as well as giving a global perspective on therapeutic alternatives. The new concept of a team approach with surgeons working together with both interventional radiologists and specialists to repair the aorta is the trademark of this book. New material and new...

Clostridium difficile, a major nosocomial pathogen shown to be a primary cause of antibiotic-associated disease, has emerged as a highly transmissible and frequently antibiotic-resistant organism, causing a considerable burden on health care systems worldwide. In Clostridium difficile: Methods and Protocols, expert...

Microalgae are one of the most studied potential sources of biofuels and bioenergy. This book covers the key steps in the production of renewable biofuels from microalgae - strain selection, culture systems, inorganic carbon utilisation, lipid metabolism and quality, hydrogen production, genetic engineering, biomass harvesting,...

This book examines one of the thorniest problems of ancient American archaeology: the origins and domestication of maize. Using a variety of scientific techniques, Duccio Bonavia explores the development of maize, its adaptation to varying climates, and its fundamental role in ancient American cultures. An appendix (by Alexander Grobman)...