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Endocannabinoids: The Brain and Body's Marijuana and Beyond
Endocannabinoids: The Brain and Body's Marijuana and Beyond

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana,  and the finding of endogenous cannabinoids, which...

Thyroid Cytopathology (Essentials in Cytopathology)
Thyroid Cytopathology (Essentials in Cytopathology)

Advances in molecular and genetics-based diagnostics are driving an increased interest in cytopathology, as cytological specimens are the ideal substrate for this new technology. Although there are a handful of comprehensive, standard texts on the market, there is a need for portable, more concise books for easy reference. Thus, the inception...

Cadmium Toxicity: New Aspects in Human Disease, Rice Contamination, and Cytotoxicity (Current Topics in Environmental Health and Preventive Medicine)
Cadmium Toxicity: New Aspects in Human Disease, Rice Contamination, and Cytotoxicity (Current Topics in Environmental Health and Preventive Medicine)
This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular...
CRISPR Guide RNA Design: Methods and Protocols (Methods in Molecular Biology, 2162)
CRISPR Guide RNA Design: Methods and Protocols (Methods in Molecular Biology, 2162)
This detailed volume focuses on the CRISPR-associated guide RNA and how it can be designed, modified, and validated for a broad repertoire of purposes. Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and...
BioMEMS and Biomedical Nanotechnology
BioMEMS and Biomedical Nanotechnology
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving theway many important genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a...
Pancreatic Cancer: Methods and Protocols (Methods in Molecular Medicine)
Pancreatic Cancer: Methods and Protocols (Methods in Molecular Medicine)
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. Pancreatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples...
The Compatibility Gene: How Our Bodies Fight Disease, Attract Others, and Define Our Selves
The Compatibility Gene: How Our Bodies Fight Disease, Attract Others, and Define Our Selves

This is the story of a few human genes and how we discovered what these genes do. We each have around 25,000 genes, but the genes in this story are those that vary the most from person to person. These genes--called compatibility genes--are, in effect, a molecular signature that distinguishes each of us as individuals. Davis tells the...

Chloroplast Biotechnology: Methods and Protocols (Methods in Molecular Biology)
Chloroplast Biotechnology: Methods and Protocols (Methods in Molecular Biology)

In Chloroplast Biotechnology: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used in chloroplast molecular biology. Chapters focus on essential background information, applications in tobacco and protocols for plastid transformation in crops and Chlamydomonas and...

Brain Damage and Repair: From Molecular Research to Clinical Therapy
Brain Damage and Repair: From Molecular Research to Clinical Therapy

This book builds a novel bridge from molecular research to clinical therapy. This approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes...

Autoimmunity: Methods and Protocols (Methods in Molecular Medicine)
Autoimmunity: Methods and Protocols (Methods in Molecular Medicine)

This collection of readily reproducible molecular techniques and related in vitro/in vivo model systems can be used to explore the causes of autoimmunity, as well as how best it may be regulated. There are methods to assess immunological and biochemical pathways relevant for pathogenesis and to establish and assess a variety of autoimmune...

Textbook of Drug Design and Discovery, Fourth Edition
Textbook of Drug Design and Discovery, Fourth Edition

The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight into lead...

Pheromones and Animal Behavior: Chemical Signals and Signatures
Pheromones and Animal Behavior: Chemical Signals and Signatures

Pheromones and other kinds of chemical communication underlie the behavior of all animals. Building on the strengths of the first edition, widely recognized as the leading text in the subject, this is a comprehensive overview of how pheromones work. Extensively revised and expanded to cover advances made over the last ten years, the book...

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