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| | Handbook of Ataxia Disorders (Neurological Disease and Therapy)
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice.
Organized by the distinctive ataxia disorders, their pathogenesis, and... | | Computer Modeling in Bioengineering: Theoretical Background, Examples and SoftwareBioengineering is a broad-based engineering discipline that applies engineering principles and design to challenges in human health and medicine, dealing with bio-molecular and molecular processes, product design, sustainability and analysis of biological systems. Applications that benefit from bioengineering include medical devices, diagnostic... |
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Brain Mapping: The Methods, Second Edition (Toga, Brain Mapping)
Investigation of the functional architecture of the human brain using modern noninvasive imaging techniques is a rapidly expanding area of research. A proper knowledge of methodology is needed to appreciate the burgeoning literature in the field. This timely publication provides an excellent catalogue of the main techniques.
... | | Animal Models of Cognitive Impairment (Frontiers in Neuroscience)
The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans.
Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of... | | Molecular Neurosurgery with Targeted Toxins
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is... |
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Molecular Computation Models: Unconventional ApproachesWith the increasing complexity of software systems and their widespread growth into many aspects of our lives, the need to search for new models, paradigms, and ultimately, technologies, to manage this problem is evident. The way nature solves various problems through processes evolving during billions of years was always an inspiration to many... | | Database Annotation in Molecular Biology: Principles and PracticeTwo factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases. The quality of the data - especially nucleic acid sequences - is satisfactory; however, annotations depend on features inferred from the data... | | |
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