Featuring a focus on mechanisms, this popular reference comprehensively covers important concepts in physiology, both at the organ system and cellular levels. Easy to read and user-friendly, the revised third edition stresses essential and relevant content with absolute clarity and includes concise step-by-step explanations complemented by...

Chapters written by basic scientists and clinicians to emphasize...

This book contains a series of contributions from internationally renowned academics with special expertise in one or other diseases which collectively are grouped under the heading myeloproliferative disorders. There have been many recent developments in understanding the pathophysiology and a number therapeutic innovations in this area. A...

256 pages, 67 figures, 6 tables, hardcover This monograph is the first of its kind to focus specifically on the role of astroglia in aging-related human neurodegenerative disorders and experimental models of CNS senescence and degeneration. As such, this volume in the Neuroscience Intelligence Unit Series represents a novel and important...

This volume provides an overview of the state of the art on the emerging cardiac pathologies such as acute coronary syndromes, atrial fibrillation, sudden death, heart failure, global cardiovascular prevention and syncope. Its chapters, written by leading experts in these fields, offer the latest information about epidemiology,...

The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development. This book consists of a compilation of chapters based on presentations at a...

'Ototoxicity' is a compendium of information on the ototoxic potential of clinically useful drugs. Each section of this thorough text is written by a leading authority in the field. The book reviews the important classes of medications known to cause ototoxicity and their mechanisms. Clinical manifestations, what is known about...

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They...

In recent years, progress in pain research has yielded substantial new insights, and this has profoundly altered our understanding of various orofacial pain conditions. Written by renowned international researchers and clinicians, this state-of-the-art textbook presents recent advances in the understanding of orofacial pain and offers...

This book clarifies and explains perineal anatomy and the pathophysiology of anal incontinence as well as applied pharmacology. It also institutes the new recommended classification of perineal tears, and describes anal sphincter repair techniques. The emphasis is on correct post-operative management, management of pregnancy following...