Learn IT - Books tags pharmaceutical

Advanced Computer-Assisted Techniques in Drug Discovery (Methods and Principles in Medicinal Chemistry)

John Wiley & Sons, 1994

The main objective of this series is to offer a practice-oriented survey of techniques currently used in Medicinal Chemistry. Following the volumes on Hansch analysis and related approaches (Vol. 1) and multivariate analyses (Vol. 2), the present handbook focuses on some new, emerging techniques in drug discovery; emphasis is...

Methods of Analysis for Functional Foods and Nutraceuticals, Second Edition

CRC Press, 2008

Functional foods and nutraceuticals encompasses a wide variety of topics ranging from foods with positive health attributes to even dietary supplements. The analysis of this diverse category can create its own set of challenges since sometimes it is not known what is the active agent. Hence an analyst looks for a marker compound,...

Biosimulation in Drug Development

John Wiley & Sons, 2007

Drug development is far from a straightforward endeavor. It starts with the identification of a pharmaceutically promising substance, the potential of which is further investigated in near-exhausting physiological analyses (Chapter 1). If it is found effective, this does not necessarily mean that we know all the molecular...

The Investigation of Organic Reactions and Their Mechanisms

John Wiley & Sons, 2007

A range of alternative mechanisms can usually be postulated for most organic chemical reactions, and identification of the most likely requires detailed investigation. Investigation of Organic Reactions and their Mechanisms will serve as a guide for the trained chemist who needs to characterise an organic chemical reaction and investigate its...

Insulin Resistance: Insulin Action and its Disturbances in Disease

John Wiley & Sons, 2005

Hormone resistance syndromes are typically thought of as rare, usually genetic, disorders with a severe but relatively stereotyped clinical and biochemical profile. While there are syndromes of severe insulin resistance that conform to this description, defective insulin action is of much more pervasive biomedical importance....

Animal Models of T Cell-Mediated Skin Diseases (Ernst Schering Foundation Symposium Proceedings)

Springer, 2004

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly...

Pharmacogenetics of Psychotropic Drugs

Cambridge University Press, 2002

This book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the findings that have already emerged. Coverage extends to antipsychotics, antidepressants and mood stabilizing, cognitive-enhancing and anxiolytic drugs. The volume also examines...

Leptin (Endocrine Updates)

Springer, 2006

The discovery of leptin by Friedman and his colleagues in 1994 was a seminal discovery in the study of metabolism, providing a new tool to study energy expenditure and appetite regulation. Early studies actively investigated many aspects of metabolism, obesity, and diabetes but it was soon evident that leptin was much more than...

Reviews in Computational Chemistry, Reviews in Computational Chemistry, Volume 18

John Wiley & Sons, 2002

This volume, like those prior to it, features chapters by experts in various fields of computational chemistry. Topics covered in Volume 18 include molecular modeling, computer-assisted molecular design (camd), quantum chemistry, molecular mechanics and dynamics, and quantitative structure-activity relationships (qsar).

After our...

Molecular Diversity in Drug Design

Springer, 1999

This book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse sets of structures. The algorithms also deal with the problem of focused diversity where...

Quality of Life: Assessment, Analysis, and Interpretation

John Wiley & Sons, 2000

'Winner of first prize in the Basis of Medicine Category of the BMA Medical Book Competition 2001'

The One Essential Comprehensive Volume on Quality of Life Research. Quality of life studies are now an essential part of the evaluation of any treatment. Written by two authors who are well respected within this...

COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)

Humana Press, 2003

The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...

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