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Modern Arylation Methods
Modern Arylation Methods

Today, arylation methods are belonging to the most important reaction types in organic synthesis. Lutz Ackermann, a young and ambitious professor has gathered a number of top international authors to present the first comprehensive book on the topic.
Starting from a historical review, the book covers hot topics like
...

Toxicology and Ecotoxicology in Chemical Safety Assessment
Toxicology and Ecotoxicology in Chemical Safety Assessment

The use of chemicals in any workplace in the developed world is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the handling and use of chemicals. In practice, those risk assessments are generally carried out by a range of...

Autonomous Robots: Modeling, Path Planning, and Control
Autonomous Robots: Modeling, Path Planning, and Control

It is at least two decades since the conventional robotic manipulators have become a common manufacturing tool for different industries, from automotive to pharmaceutical. The proven benefits of utilizing robotic manipulators for manufacturing in different industries motivated scientists and researchers to try to extend the applications of...

Acne and Its Therapy (Basic and Clinical Dermatology)
Acne and Its Therapy (Basic and Clinical Dermatology)

Addressing one of the most commonly encountered conditions seen by the dermatologist, this source analyzes the pathophysiology, evaluation, diagnosis, clinical features, and control of acne. With full-color illustrations, this source delves into the available treatment options for difficult cases of acne and scarring and provides expert...

Essentials Of Chemical Biology: Structure and Dynamics of Biological Macromolecules
Essentials Of Chemical Biology: Structure and Dynamics of Biological Macromolecules

“This excellent work fills the need for an upper-level graduate course resource that examines the latest biochemical, biophysical, and molecular biological methods for analyzing the structures and physical properties of biomolecules… This reviewer showed [the book] to several of his senior graduate students, and they...

Access to Knowledge in the Age of Intellectual Property
Access to Knowledge in the Age of Intellectual Property

At the end of the twentieth century, intellectual property rights collided with everyday life. Expansive copyright laws and digital rights management technologies sought to shut down new forms of copying and remixing made possible by the Internet. International laws expanding patent rights threatened the lives of millions of people around the...

Iron Metabolism: From Molecular Mechanisms to Clinical Consequences
Iron Metabolism: From Molecular Mechanisms to Clinical Consequences

Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between...

Pharmacogenetics of Psychotropic Drugs
Pharmacogenetics of Psychotropic Drugs

This book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the findings that have already emerged. Coverage extends to antipsychotics, antidepressants and mood stabilizing, cognitive-enhancing and anxiolytic drugs. The volume also examines...

The Investigation of Organic Reactions and Their Mechanisms
The Investigation of Organic Reactions and Their Mechanisms

A range of alternative mechanisms can usually be postulated for most organic chemical reactions, and identification of the most likely requires detailed investigation. Investigation of Organic Reactions and their Mechanisms will serve as a guide for the trained chemist who needs to characterise an organic chemical reaction and investigate its...

Insulin Resistance: Insulin Action and its Disturbances in Disease
Insulin Resistance: Insulin Action and its Disturbances in Disease
Hormone resistance syndromes are typically thought of as rare, usually genetic, disorders with a severe but relatively stereotyped clinical and biochemical profile. While there are syndromes of severe insulin resistance that conform to this description, defective insulin action is of much more pervasive biomedical importance....
Animal Models of T Cell-Mediated Skin Diseases (Ernst Schering Foundation Symposium Proceedings)
Animal Models of T Cell-Mediated Skin Diseases (Ernst Schering Foundation Symposium Proceedings)

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly...

Biosimulation in Drug Development
Biosimulation in Drug Development
Drug development is far from a straightforward endeavor. It starts with the identification of a pharmaceutically promising substance, the potential of which is further investigated in near-exhausting physiological analyses (Chapter 1). If it is found effective, this does not necessarily mean that we know all the molecular...
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