This volume, written by a range of international experts, covers a wide range of topics involving organic fluorine compounds. Each chapter is preceded by a summary and includes extensive illustrations and references. The chapters cover atmospheric chemistry, application of 19F NMR, partition, degradation and transformation, naturally occurring organic fluorine compounds, toxicology of perfluoroalkanes and phosphorofluoridates, and application of aromatic compounds to the elucidation of the mechanism of cytochrome P450.

Fluorine occurs naturally in only a few organic compounds. In the chemical industry fluorine is a substituent of choice used to modify synthetic substrates in expectation of conferring beneficial physical properties.When incorporated, the spectroscopic properties of fluorine make it a useful tool to aid the structural elucidation of the derived substances. Fluorine is generally resistant to degradation and offers interesting possibilities as a probe for the determination of chemical residues and the investigation of metabolic processes. This chapter offers an overview of the ways in which the many recent advances in NMR technology can be exploited to derive useful qualitative and quantitative chemical information from fluorinated substances.