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Controlled Genetic Manipulations (Neuromethods, Vol. 65)
Controlled Genetic Manipulations (Neuromethods, Vol. 65)

The current demand for the development of techniques for controlled genetic manipulations is driven by the anatomical and physiological complexity of the brain and by the need for experimental models that can address this complexity through selective manipulation of defined components of the system: specific neuronal populations or selected...

Epidermal Cells: Methods and Protocols (Methods in Molecular Biology Series)
Epidermal Cells: Methods and Protocols (Methods in Molecular Biology Series)

A collection of cutting-edge methods to analyze and manipulate epidermal cellprecursors and mature epidermal cells. These protocols cover different methods and models for culturing epidermal cells, for enriching very early epidermal progenitors, and for studying epidermal cell commitment and differentiation both in vitro and in vivo. Topics...

Laser Capture Microdissection: Methods and Protocols (Methods in Molecular Biology)
Laser Capture Microdissection: Methods and Protocols (Methods in Molecular Biology)

Expert laboratorians noted for their optimized methods describe in step-by-step detail how to successfully carry out tissue-based laser microdissection in their own laboratory using the different systems available and to apply a wide range of sophisticated molecular technologies to the microdissected tissue samples. Highlights include gene...

Urological Emergencies: A Practical Guide (Current Clinical Urology)
Urological Emergencies: A Practical Guide (Current Clinical Urology)

Practicing urologists and leading specialists summarize the optimal management of urgent and emergent urological conditions, so that physicians with limited urological training can take advantage of the incredible improvements in the management of acute urological problems. Up-to-date, evidence-based descriptions of the optimal diagnostic and...

Proteasome Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
Proteasome Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)

A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome...

Handbook of Drug'Nutrient Interactions (Nutrition and Health)
Handbook of Drug'Nutrient Interactions (Nutrition and Health)

This benchmark survey of drug-nutrient interactions details the mechanisms and clinical approaches to their effective management. Providing more than a simple listing of common interactions, the authors explore, in-depth, every major aspect of the problem, including drug and nutrient disposition, enzyme systems, the effects of nutritional...

Stem Cell Biology and Regenerative Medicine in Ophthalmology
Stem Cell Biology and Regenerative Medicine in Ophthalmology
In the last few decades, stem cell research has developed groundbreaking technologies to both study and treat diseases. This research has proven fruitful for the field of ophthalmology, especially in recent years. With its relative immune privilege, the eye has proven an ideal testing ground for stem cell therapies.

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Nanoscale Imaging of Synapses: New Concepts and Opportunities (Neuromethods)
Nanoscale Imaging of Synapses: New Concepts and Opportunities (Neuromethods)

Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to study them with traditional techniques. Fortunately, recent ground-breaking advances in optical microscopy (e.g....

Histopathology: Methods and Protocols (Methods in Molecular Biology)
Histopathology: Methods and Protocols (Methods in Molecular Biology)

Histopathology: Methods and Protocols provides a comprehensive guide to the current issues in histopathology. With chapters on organ-based approaches with specific protocols for morphologic, molecular examination and pathological observations governing the therapeutic management of the diseases. Written in the highly successful...

The Myc Gene: Methods and Protocols (Methods in Molecular Biology)
The Myc Gene: Methods and Protocols (Methods in Molecular Biology)

Myc controls multiple cellular functions, including cell proliferation, growth, differentiation and death, both directly and indirectly, through its modulation of downstream transcriptional programs. In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc...

Cytoskeleton Dynamics: Methods and Protocols (Methods in Molecular Biology)
Cytoskeleton Dynamics: Methods and Protocols (Methods in Molecular Biology)

This volume details comprehensive state-of-the-art methods on actin microfilaments and microtubules and how they work to achieve different cellular functions in different cellular contexts. Chapters guide readers through protein purification, in vitro reconstitution of several cytoskeleton properties, analyses of microtubule- and...

Computational Neuroanatomy: Principles and Methods
Computational Neuroanatomy: Principles and Methods
"...a useful addition to major neuroscience libraries." -Neuroradiology

In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain.
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