The name "random walk" for a problem of a displacement of a point in a sequence of independent random steps was coined by Karl Pearson in 1905 in a question posed to readers of "Nature". The same year, a similar problem was formulated by Albert Einstein in one of his Annus Mirabilis works. Even earlier such a problem was...

Estuaries are among the most biologically productive ecosystems on the planet--critical to the life cycles of fish, other aquatic animals, and the creatures which feed on them. Estuarine Ecology, Second Edition, covers the physical and chemical aspects of estuaries, the biology and ecology of key organisms, the flow of organic matter...

The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in the reductionist approaches to understanding and manipulating the acute inflammatory response in the settings of sepsis,...

Expert laboratorians update the classic bioconjugation methods and introduce valuable new techniques that go beyond pure biomedical applications to include elements from advanced organic synthesis, molecular biology, and materials science. These readily reproducible methods cover the preparation of protein conjugates using covalent and...

The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow,...

Electrotherapy is fast gaining mainstream acceptance, no doubt due to the growing mountain of clinical evidence demonstrating its effectiveness. To meet the growing demand for information, this scientifically rigorous guide gives healthcare professionals and engineers essential technical, biological, and clinical background together with...

A collection of classic, novel, and state-of-the-art methods for the study of cell migration in cultured cells, different model organisms, and specialized cells in normal development and disease. Highlights include basic assays that apply to all cell migration studies in vitro, assays in various model organisms, and assays for cancer cells,...

The third volume of the "Practice of Intramedullary Locked Nails" places a special focus on recent advancements in understanding the biology of fracture healing of long bones, the emerging technologies that further enhance the minimally invasive nature of closed treatment of fractures, and the availability of various surgical...

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this...