Macrophages are an important part of the immune response and are characterized by their ability to phagocytose foreign matter. However the difficulties involved in macrophage isolation mean they are some of the body's least explored cells. Macrophage Methodology describes how to isolate moderate to high yields of viable cells...
Thoroughly revised for its Third Edition, this volume is the most comprehensive, multidisciplinary text on genitourinary cancers. This edition has two new editors—Frans M.J. Debruyne and W. Marston Linehan—and more than 50% new contributors. Seventeen new chapters cover familial prostate cancer, biology of bone...
30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics...
Copper (Cu), an essential trace element, is required for the survival of organisms
ranging from bacteria to mammals. Because Cu ions can adopt distinct redox states (oxidized
Cu[II] or reduced Cu[I]), they play a pivotal role in cell physiology as catalytic
cofactors in the redox chemistry of enzymes involved in a broad spectrum of...
Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which...
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer
death in the United States. Annually approximately 30,000 Americans are
diagnosed with the disease and most will die from it within five years. Pancreatic
ductal adenocarcinoma is unique because of its late onset in age, high
mortality, small tumor samples...
Practicing evidenced-based medicine some 25 centuries ago, Hippocrates proclaimed "Let food be thy medicine and medicine be thy food." This advice parallels the common American saying, "You are what you eat," and is supported by a National Institute of Health recommendation to consume as many as eight servings of fruits...
Cytokines and chemokines are an important class of effector molecules that play a fundamental
role in orchestrating the innate and acquired immune responses needed to eliminate or
wall off invading pathogens. In vitro and in vivo studies have been instrumental in revealing
the complexity of the cytokine network and the many facets of...
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics including RUNX Genes in Development and Cancer; The RNA Continent; The c-myc Promoter; Designer Self-Assembling Peptide Nanofiber...
The concept that cancer stem cells play an important role in malignant
tumors is gaining more and more support due to recent advances in
the field. The latest progress in this area is increasingly reported and
commented on in the lay press, documenting the high excitement and
hopes it generates.
This lavishly illustrated unique atlas provides a comprehensive and up-to-date overview of FAF imaging in retinal diseases. It also compares FAF findings with other imaging techniques such as fundus photograph, fluorescein- and ICG angiography as well as optical coherence tomography. General ophthalmologists as well as retina specialists will...
This book summarizes the keynote and plenary speeches and posters of the “Xth
International Nidovirus Symposium: Toward Control of SARS and Other Nidovirus
Diseases” that was held in Colorado Springs, Colorado, June 25–30, 2005. The nine
previous meetings of scientists investigating the molecular biology and...
