This volume focusses on the current evidence surrounding the use of endovascular therapy. It updates and complements the earlier Medical Radiology volume on the Radiology of Peripheral Vascular Diseases. Some background information is provided on vascular biology and the facilities required for safe endovascular practice, along with guidance...

With sequencing of the human genome now complete, deciphering the role of gene function in human neurological pathophysiology is a promise that has yet to be realized. More than most diseases, stroke has been keenly studied from a genomic perspective. Studies are numerous and incorporate data on stroke inheritance, chromosomal loci of risk,...

Thoroughly revised and expanded, this accessible single-volume reference features a foreword by an expert in neuropsychology and will serve lay readers and medical professionals alike. More than 600 clear, concise entries explore such topics as the anatomy of the brain; the role of the brain in the central nervous system; how thoughts,...

In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of...

This volume presents the latest global knowledge of thyroid disorders in infancy, childhood, and adolescence and represents experience and views from a panel of the world’s most renowned authorities on thyroid pathophysiology and clinical entities in the pediatric population. Both basic science and clinical aspects of thyroid disease...

Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic cellular processes. Among these important roles is the regulation of cellular...

Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that...

The aim of this volume is to underline that promoting physical activity is crucial to preventing illness and maintaining our health, thus leading to a reduction in healthcare costs. Over the last decade studies have shown that physical exercise plays an important role in maintaining an individual's psycho-physical balance. Physical...

2-D and 3-D anal ultrasound are among the most recent and advanced tools available for both the diagnosis and the management of anorectal diseases. They are neither expensive nor harmful for the patients and progressively replaced anal mapping with EMG electrodes for the diagnosis of sphincter's defects and anismus, which represents...