In March 1998, we presented to our clients a technical report entitled En skalbar arkitektur. We wrote it in Swedish, which is our native language. Its purpose was to offer ideas for designing and developing scalable Microsoft Windows applications, using tools such as Microsoft Visual Basic 5.0 and Microsoft Transaction Server (MTS) and...
Chromatin is of central importance to gene regulation in eukaryotes. Reflecting this singular role for chromatin, numerous approaches have evolved in the laboratory over the past three decades to study chromatin structure and its alterations. Methods of investigating chromatin remodeling, whether in changes in nucleosome structure or...
The evolution of modern cell biology tools, such as confocal imaging techniques and advanced electron microscopy methodologies, has allowed for ever improving structural and functional characterizations of the cell. Such methods complement classical genetics and biochemistry in the ongoing effort to define cellular science. This...
Biotechnology is one of the major new technologies of the twenty-first century that covers multi-disciplinary issues, including DNA techniques, cloning, genetics, and the application of microbiology to the production of goods. It continues to revolutionize the treatments of many diseases, and it is used to deal with environmental solutions....
As computing devices proliferate, demand increases for an understanding of emerging computing paradigms and models based on natural phenomena. Neural networks, evolution-based models, quantum computing, and DNA-based computing and simulations are all a necessary part of modern computing analysis and systems development. Vast literature exists on...
This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization....
In the late 1990s, the widespread availability of low-cost computers and access to global connectivity have fueled the demand for a new kind of application: the highly distributed application. Highly distributed applications are used by extremely large numbers of people around the world who are connected to many application and data servers...
This volume shows the current state of the art, and the science, of evolutionary creativity. It shows what can--and equally important, what can't--be done at the turn of the new millennium. What will have been achieved by the turn of the next one is anyone's guess. Meanwhile, it's intriguing, it's instructive, it's difficult, and it's fun!...
Molecular Forensics offers a comprehensive coverage of the increasingly important role that molecular analysis plays within forensic science. Starting with a broad introduction of modern forensic molecular technologies, the text covers key issues from the initial scenes of crime sampling to the use of evidential material in the...
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated...
"Combinatorics is one of the fastest growing fields of mathematics. … From the table of contents one can see the wide range of topics covered. The authors are acknowledged researchers of the presented fields and guarantee the high quality of the volume. If you want to be up-to-date in combinatorics you should...
Since the concept of the first DNA biochip, biotechnologies have soared, deeply
changing the world of biology. In fact, they have already had direct implications on
each of us. Since the very beginning of this science in the 1980s, spectacular
advances have been made, such as the analysis of the human DNA genome
sequence, while...
