A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated...
This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization....
Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the National Institute of Aging convened a program involving several leading gerontological...
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first...
This book covers topics that range from fundamental studies of DNA replication, chromosomal and nuclear function through growth factor control of endocrine tumor initiation and progression. The basic and translational insights gained from Hormonal Control of Cell Cycle will be of interest to those studying the biology of endocrine tumors as...
Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial.
Chapters in part one focus on the fundamentals and properties of porous...
Updating researchers on phenomenal progress in the field of molecular medicine the Encyclopedia of Medical Genomics and Proteomics offerstrail-blazing studies and authoritative contributions from more than 400 specialists. An important and timely contribution to the biomedical community, the encyclopedia compiles...
The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing...
One of the most significant areas of advance in clinical medicine over the last 20 years has been in the imaging technologies. It is difficult to point to the single method or application that has benefited most from those advances because nearly all specialities in medicine have been involved. Perhaps the most significant trend, however, has...
Forensic taphonomy is the study of the postmortem changes to human remains, focusing largely on environmental effectsâincluding decomposition in soil and water and interaction with plants, insects, and other animals. While other books have focused on subsets such as forensic botany and entomology, Manual of Forensic Taphonomy is...
This book provides a comprehensive, up-to-date overview of the opportunities and challenges of the complex field of synthetic biology, which combines various scientific disciplines. The emerging field of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular...
A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity,Volume 2: In Vivo Models, Imaging, and Molecular Regulators contains cutting-edge protocols for classifying tumors...
