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Iminosugars: From Synthesis to Therapeutic Applications
The field of iminosugars is a very exciting area of research. These carbohydrate mimetics
were first imagined and synthesized by chemists in the 1960s before being isolated from
Nature a few years later. Since the discovery of their biological activity as potent glycosidase
inhibitors in the 1970s, iminosugars have been the subject... | | | | Digital Evidence and Computer Crime, Second EditionDigital evidence--evidence that is stored on or transmitted by computers--can play a major role in a wide range of crimes, including homicide, rape, abduction, child abuse, solicitation of minors, child pornography, stalking, harassment, fraud, theft, drug trafficking, computer intrusions, espionage, and terrorism.
Though an... |
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Chemotherapy-Induced Neuropathic Pain
There have been tremendous recent advances in the pharmacotherapy, dose regimens, and combinations used to treat cancer and for the treatment or prevention of the spread of disease. As a direct result of these advances, there are an increasing number of cancer survivors, although research dealing with chemotherapy-induced pain is still in its... | | Thrombolytic Therapy for Stroke
The world's leading experts detail the basic rationale, scientific evidence, and treatment protocol for thrombolytic therapy in acute stroke patients. These experienced clinicians show how promptly delivered thrombolysis can restore cerebral blood flow in time to salvage brain and neurologic functions, first by reviewing the preclinical... | | Antisense Therapeutics (Methods in Molecular Medicine)
A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include... |
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