Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in...
There is a perception in the scientific community that the discipline of Physiology
is in crisis, or at least, in a phase of profound transition and change. At the root of
the problem is confusion between objectives (the biological questions to be solved)
and the methods and technologies to be applied. Traditionally, ever since...
This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description...
Established for fifteen years as the standard work in the field, Melvin Lewis's Child and Adolescent Psychiatry: A Comprehensive Textbook is now in its Fourth Edition. Under the editorial direction of Andrés Martin and Fred R. Volkmar—two of Dr. Lewis's colleagues at the world-renowned Yale Child Study...
Angiogenesis is of fundamental importance in development, health, and disease. The
study of angiogenesis in the eye, in particular, has increased exponentially in the last
decade because retinal and choroidal neovascularization play an important role in the
major blinding diseases of the industrialized world and represent an...
The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...
To appreciate the dangers and the risks from chemicals of all kinds it is
necessary to understand how, when and why they are toxic. This falls
within the field of toxicology and is what this book is all about.
I was encouraged to write the book by Dr John Emsley, who is well
known for his popular science books on...
This book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse sets of structures. The algorithms also deal with the problem of focused diversity where...
This is the first part in a two-volume work on neuromodulation. It describes techniques and procedures applied in internal contact with non-neural tissues surrounding the nervous system (dura or cerebrospinal fluid), as in the case of epidural stimulation for pain or intrathecal drug application for the treatment of spasticity and pain. In...
The hybrid/heterogeneous nature of future microprocessors and large high-performance computing systems will result in a reliance on two major types of components: multicore/manycore central processing units and special purpose hardware/massively parallel accelerators. While these technologies have numerous benefits, they also pose substantial...
This book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the findings that have already emerged. Coverage extends to antipsychotics, antidepressants and mood stabilizing, cognitive-enhancing and anxiolytic drugs. The volume also examines...
Unless you’re a hermit, chances are good that your life is touched by SAS (pronounced “sass”) almost every day.
Have you ever received an offer for a credit card in the mail? The bank might have used SAS to select you for the particular offer you received. Remember a recent news article that cited demographic...
