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Synthetic Multivalent Molecules: Concepts and Biomedical Applications
Synthetic Multivalent Molecules: Concepts and Biomedical Applications
This book presents basic and advanced principles underlying the multivalent interactions that are prevalent in biological systems. To illustrate important or complex concepts, the book provides up-to-date examples of synthetic multivalent molecules, their design, and their biological benefits. Functional roles displayed by such...
Diabetes: The Biography (Biographies of Diseases)
Diabetes: The Biography (Biographies of Diseases)

Diabetes is a disease with a fascinating history and one that has been growing dramatically with urbanization. According to the World Health Authority, it now affects 4.6% of adults over 20, reaching 30% in the over 35s in some populations. It is one of the most serious and widespread diseases today. But the general perception of diabetes is...

Pharmaceutical Process Scale-Up, Second Edition (Drugs and the Pharmaceutical Sciences)
Pharmaceutical Process Scale-Up, Second Edition (Drugs and the Pharmaceutical Sciences)
Scale-up is generally defined as the process of increasing batch size. Scale-up of a process can also be viewed as a procedure for applying the same process to different output volumes. There is a subtle difference between these two definitions: batch size enlargement does not always translate into a size increase of the...
Protein Tyrosine Kinases: From Inhibitors to Useful Drugs (Cancer Drug Discovery and Development)
Protein Tyrosine Kinases: From Inhibitors to Useful Drugs (Cancer Drug Discovery and Development)

Leading researchers, from the Novartis group that pioneered Gleevec/Glivec™ and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases,...

Natural Products: Drug Discovery and Therapeutic Medicine
Natural Products: Drug Discovery and Therapeutic Medicine

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the...

Cell-Penetrating Peptides:  Processes and Applications
Cell-Penetrating Peptides: Processes and Applications

One of the major problems with drug delivery is the inability of large hydrophilic compounds to pass through the lipid membrane of the cell, thus making drugs such as polypeptides and oligonucleotides of limited therapeutic value. Until recently, the transport of such molecules into the cytoplasmic and nuclear compartments of living cells...

Infectious Disease Informatics
Infectious Disease Informatics

Infectious Diseases Informatics

Edited by

Vitali Sintchenko

The University of Sydney, Sydney, Australia

Preface.- List of contributors.- 1Informatics for Infectious Disease Research and Control.- 2 Bioinformatics of Microbial Sequences.- 3 Mining Databases for Microbial Gene Sequences.- 4 Comparative Genomics of...

The Encyclopedia of Sleep and Sleep Disorders, Second Edition
The Encyclopedia of Sleep and Sleep Disorders, Second Edition

Millions of people have experienced sleeprelated concerns, and millions more suffer from serious sleeping disorders. The lack of proper rest can lead to fatigue at work, affect alertness while driving as well as other serious physical and mental health problems. Written for both the lay reader and the professional, The Encyclopedia of Sleep and...

What If Medicine Disappeared?
What If Medicine Disappeared?

I was trying to imagine what the world would look like without Western medicine. Gone would be primary care physicians, surgeons, psychiatry—all the various medical specialties. There would be no treatment for trauma, nor fractures. Sufferers from the common cold would need to recover without their physician’s help. There would be...

Pharmacodynamic Basis of Herbal Medicine
Pharmacodynamic Basis of Herbal Medicine

HERBAL MEDICINE FROM A WESTERN POINT OF VIEW

Herbal remedies have become a major factor in American health care. Botanicals like Ginseng, Ma Huang, St. John's Wort, and Valerian are now household words throughout the world. Since many of these natural drugs are sold over the counter, often consumers mistakenly assume that
...

Web Search Garage
Web Search Garage

Best-selling author and research expert Tara Calishain offers her insider tips and tricks for web searching in this title from Prentice Hall PTR's Garage Series. The book begins with an in-depth look at search engines and other online tools such as browsers. It describes several principles of web searching to help you leverage the scope of the...

Beyond Red and Blue: How Twelve Political Philosophies Shape American Debates
Beyond Red and Blue: How Twelve Political Philosophies Shape American Debates
On any given night cable TV news will tell us how polarized American politics is: Republicans are from Mars, Democrats are from Canada. But in fact, writes Peter Wenz in Beyond Red and Blue, Americans do not divide neatly into two ideological camps of red/blue, Republican/Democrat, right/left. If they did, what could explain Republicans...
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