Tumor angiogenesis is one of the most prominent mechanisms driving tumor development and progression. This book is written by internationally renowned experts. Part 1 describes the basic mechanisms. Tumor-angiogenic signaling pathways are presented as new potential targets for anti-angiogenic therapy. Part 2 reviews the efforts made to...

Collective knowledge of the origins and pharmacology of pain are evolving rapidly, providing increased hope for better pain management and a far greater quality of life for patients worldwide. However, there are few works dedicated to guiding primary care practitioners and clinical researchers through the use of adjuvant analgesics. Part of...

Blood Science is a relatively new discipline which merges biochemistry, haematology, immunology, transfusion science and genetics. This bringing together of traditional disciplines requires a corresponding change in education and training for healthcare scientists and Blood Science: Principles and Pathology is written in response to this...

The book's three main sections examine the nature of addiction, including...

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental...

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems.
Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination...

Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to...

This book focuses on efficacy, toxicity, drug interactions, and abnormal clinical laboratory tests resulting from the use of herbal remedies. Although a few herbal remedies are safe and have efficacy (for example saw palmetto), many herbal remedies are toxic. This book guides in the interpretation of abnormal test results in otherwise healthy...

Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made...

Now the publishers of the most accurate reference for FDA-approved drug information brings you the complete, authoritative...

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as...