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Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Over the past three decades the field of immunotoxicology, the study of the effects of exposure to drugs, chemicals, or physical/environmental agents on the structure and function of the immune system has benefited from an increasingly detailed understanding of the cellular and molecular basis of innate and acquired immunity....
Streptomyces in Nature and Medicine: The Antibiotic Makers
Streptomyces in Nature and Medicine: The Antibiotic Makers

This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth...

COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)
COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)

The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...

Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Targeted Therapies in Cancer: Myth or Reality? (Advances in Experimental Medicine and Biology)
Cancers share a restricted set of characteristics crucial to the tumor phenotype: proliferation in the absence of external growth stimuli, avoidance of apoptosis and no limits to replication, escape from external growth-suppressive forces and the immune response, an inflammatory micro-environment with new blood vessel...
Cancer Drug Resistance (Cancer Drug Discovery and Development)
Cancer Drug Resistance (Cancer Drug Discovery and Development)

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport,...

Contrast Agents III: Radiopharmaceuticals - From Diagnostics to Therapeutics (Topics in Current Chemistry) (v. 3)
Contrast Agents III: Radiopharmaceuticals - From Diagnostics to Therapeutics (Topics in Current Chemistry) (v. 3)
It is the objective of this review to introduce the reader to the current status of organometallic chemistry, oriented towards the development of novel 99mTc-based imaging agents. This type of inorganic chemistry has nowadays become part of so-called bioorganometallic chemistry.

The article describes the current
...
Hysteroscopy: Visual Perspectives of Uterine Anatomy, Physiology, and Pathology
Hysteroscopy: Visual Perspectives of Uterine Anatomy, Physiology, and Pathology

Thoroughly revised, updated, and expanded, the Third Edition of Diagnostic and Operative Hysteroscopy provides a comprehensive pictorial and textual guide to the anatomy, physiology, pathology, and clinical aspects of the uterus and the latest diagnostic and operative hysteroscopy procedures. This edition features more than...

Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 2nd Edition
Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 2nd Edition

This second edition of the most complete parent guide available, features detailed and precise medical information about solid tumor childhood cancers, including neuroblastoma, Wilms tumor, liver tumors, soft tissue sarcomas, and bone sarcomas. In addition, it offers day-to-day practical advice on how to cope with procedures,...

Sex, Lies, and Menopause: The Shocking Truth About Synthetic Hormones and the Benefits of Natural Alternatives
Sex, Lies, and Menopause: The Shocking Truth About Synthetic Hormones and the Benefits of Natural Alternatives

Turning thirty years of medical and cultural wisdom on its head, Sex, Lies, and Menopause challenges both the medical establishment and modern feminists to prove that menopause does not have to be deadly.

In this revolutionary work -- a landmark that signals the true beginning of feminist medicine -- a doctor, a...

Hypertension Primer: The Essentials of High Blood Pressure
Hypertension Primer: The Essentials of High Blood Pressure
We are delighted to bring you the Hypertension Primer, Third Edition, a decade after the First Edition was launched. Given the breadth and depth of information available in the continuously expanding field of hypertension, our Primer remains a...
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volume 1
The aim of Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms is to present recent developments in cell survival and apoptotic pathways and their involvement in human diseases, such as cancers and neurodegenerative disorders. This requires an integration of knowledge from several fields of research, including...
The Adrenergic Receptors in the 21st Century (The Receptors)
The Adrenergic Receptors in the 21st Century (The Receptors)
Our understanding of adrenergic function has advanced considerably in the 15 years since three adrenergic receptor books were published in The Receptors series. In the late 1980s, many of the adrenergic subtypes had not yet been cloned. Most of the studies during that time focused on traditional pharmacological approaches in...
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