As the number of forensic science and forensic chemistry degree programs has increased over the last few years, Forensic Chemistry was the first book to specifically address this rapidly growing field. It introduces the principal areas of study from the perspective of analytical chemistry, addressing the legal context in which forensic...
In 1999, my colleagues and I performed a study in 7
hospitals in different regions throughout Spain where 305
patients were questioned about their use of antimigraine
medications [1] . The patients reported previous use of the
following acute agents: analgesics (99%), nonsteroidal antiinfl
ammatory drugs (NSAIDs, 69%),...
The so-called “green wave”, triggered by a growing ecological awareness, has resulted in
an increased interest in herbal formulations throughout the world, particularly in the last
decade. The consumption of medicinal plants has almost doubled in the West during that
period. The efficacy of a number of herbal formulations...
This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.
This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug transporters and...
Over the next decade, the global number of people with diabetes and at risk of diabetes and cardiovascular disease is expected to grow by 25%, largely driven by the rising prevalence of obesity and inactivity. The problem is especially serious in Asia, where the WHO predicts that in less than a decade, 60% of the worldwide population with...
Chiral amines are powerful pharmacophores for defining new pharmaceutical drugs (Figure P.1) due to their high density of structural information and inherent ability for hydrogen bonding, yet their synthesis remains a challenge. That challenge is further appreciated when framed in the context of the following goal: the introduction of...
The wealth of insights into the brain’s functioning gained by neuroscience in recent years led to the development of new possibilities for intervening in the brain such as neurotransplantation, neural prostheses and brain stimulation techniques. Moreover, new and safer classes of psychopharmaceutical drugs lend themselves to...
This is a comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The book consists of a general part dealing with themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. The second part includes the...
With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets will escalate at an even greater rate than that observed in recent years. However, identification of a potential target is only part of the process in developing these new next generation...
‘The conjugations may well be the most important drug biotransformation reactions.’ Thus reads the first sentence in Chapter 1 of this book; and indeed, this may be little realized, if one compares the overwhelming attention paid to cytochrome P-450-mediated biotransformation with what is published on the conjugations. Yet, oxidative...
âNeurocysticercosis (neural infection by larvae of Taenia solium) occurs when humans become intermediate hosts of the tapeworm Taenia solium after ingesting its eggs. The disease is now the most common helminthic infection of the nervous system in humans, and its prevalence has risen significantly even in countries where it was...
