DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for...
A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the...
Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter...
Addiction Counseling Review: Preparing for Comprehensive, Certification, and Licensing Examinations offers a clear, readable overview of the knowledge and skills those training as alcohol or other drug counselors need to pass their final degree program, certification, and licensing examinations. It is organized into six sections: Addiction...
In the context of global efforts to control the production, distribution, and use of narcotic drugs, China's treatment of the problem provides an important means of understanding the social, political, and economic limits of national and international policies to regulate drug practices. In the nineteenth and early twentieth centuries, China was...
This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug...
As the number of forensic science and forensic chemistry degree programs has increased over the last few years, Forensic Chemistry was the first book to specifically address this rapidly growing field. It introduces the principal areas of study from the perspective of analytical chemistry, addressing the legal context in which forensic...
In 1999, my colleagues and I performed a study in 7
hospitals in different regions throughout Spain where 305
patients were questioned about their use of antimigraine
medications [1] . The patients reported previous use of the
following acute agents: analgesics (99%), nonsteroidal antiinfl
ammatory drugs (NSAIDs, 69%),...
The so-called “green wave”, triggered by a growing ecological awareness, has resulted in
an increased interest in herbal formulations throughout the world, particularly in the last
decade. The consumption of medicinal plants has almost doubled in the West during that
period. The efficacy of a number of herbal formulations...
This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.
Over the next decade, the global number of people with diabetes and at risk of diabetes and cardiovascular disease is expected to grow by 25%, largely driven by the rising prevalence of obesity and inactivity. The problem is especially serious in Asia, where the WHO predicts that in less than a decade, 60% of the worldwide population with...
Chiral amines are powerful pharmacophores for defining new pharmaceutical drugs (Figure P.1) due to their high density of structural information and inherent ability for hydrogen bonding, yet their synthesis remains a challenge. That challenge is further appreciated when framed in the context of the following goal: the introduction of...
