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DNA Topoisomerases and Cancer (Cancer Drug Discovery and Development)
DNA Topoisomerases and Cancer (Cancer Drug Discovery and Development)

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for...

Drugs of Abuse: Body Fluid Testing (Forensic Science and Medicine)
Drugs of Abuse: Body Fluid Testing (Forensic Science and Medicine)

A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the...

The Effects of Drug Abuse on the Human Nervous System (Neuroscience-Net Reference Books)
The Effects of Drug Abuse on the Human Nervous System (Neuroscience-Net Reference Books)

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter...

Addiction Counseling Review: Preparing for Comprehensive, Certification, and Licensing Examinations
Addiction Counseling Review: Preparing for Comprehensive, Certification, and Licensing Examinations
Addiction Counseling Review: Preparing for Comprehensive, Certification, and Licensing Examinations offers a clear, readable overview of the knowledge and skills those training as alcohol or other drug counselors need to pass their final degree program, certification, and licensing examinations. It is organized into six sections: Addiction...
China's Drug Practices and Policies: Regulating Controlled Substances in a Global Context
China's Drug Practices and Policies: Regulating Controlled Substances in a Global Context

In the context of global efforts to control the production, distribution, and use of narcotic drugs, China's treatment of the problem provides an important means of understanding the social, political, and economic limits of national and international policies to regulate drug practices. In the nineteenth and early twentieth centuries, China was...

Chromatin and Disease (Subcellular Biochemistry)
Chromatin and Disease (Subcellular Biochemistry)

This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug...

Forensic Chemistry
Forensic Chemistry

As the number of forensic science and forensic chemistry degree programs has increased over the last few years, Forensic Chemistry was the first book to specifically address this rapidly growing field. It introduces the principal areas of study from the perspective of analytical chemistry, addressing the legal context in which forensic...

Using Patient-Friendly Composite Endpoints to Measure the Success of Acute Migraine Medications: 4th Annual Migraine Meeting, Budapest, October 2004: Proceedings (European Nephrology)
Using Patient-Friendly Composite Endpoints to Measure the Success of Acute Migraine Medications: 4th Annual Migraine Meeting, Budapest, October 2004: Proceedings (European Nephrology)
In 1999, my colleagues and I performed a study in 7 hospitals in different regions throughout Spain where 305 patients were questioned about their use of antimigraine medications [1] . The patients reported previous use of the following acute agents: analgesics (99%), nonsteroidal antiinfl ammatory drugs (NSAIDs, 69%),...
Bioassay Techniques for Drug Development
Bioassay Techniques for Drug Development

The so-called “green wave”, triggered by a growing ecological awareness, has resulted in an increased interest in herbal formulations throughout the world, particularly in the last decade. The consumption of medicinal plants has almost doubled in the West during that period. The efficacy of a number of herbal formulations...

G Protein-Coupled Receptors: Structure, Function, and Ligand Screening (Methods in Signal Transduction Series)
G Protein-Coupled Receptors: Structure, Function, and Ligand Screening (Methods in Signal Transduction Series)

This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.

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Nutritional Management of Diabetes Mellitus and Dysmetabolic Syndrome: 11th Nestlé Nutrition Workshop, Hangzhou, October-November 2005 (Nestlé ... Clinical & Performance Program, Vol. 11)
Nutritional Management of Diabetes Mellitus and Dysmetabolic Syndrome: 11th Nestlé Nutrition Workshop, Hangzhou, October-November 2005 (Nestlé ... Clinical & Performance Program, Vol. 11)

Over the next decade, the global number of people with diabetes and at risk of diabetes and cardiovascular disease is expected to grow by 25%, largely driven by the rising prevalence of obesity and inactivity. The problem is especially serious in Asia, where the WHO predicts that in less than a decade, 60% of the worldwide population with...

Chiral Amine Synthesis: Methods, Developments and Applications
Chiral Amine Synthesis: Methods, Developments and Applications

Chiral amines are powerful pharmacophores for defining new pharmaceutical drugs (Figure P.1) due to their high density of structural information and inherent ability for hydrogen bonding, yet their synthesis remains a challenge. That challenge is further appreciated when framed in the context of the following goal: the introduction of...

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