At 90 nm, wires account for nearly 75% of the total delay in a circuit. Even more insidious, however, is that among nearly 40% of these nets, more than 50% of their total net capacitance are attributed to the cross-coupling capacitance between neighboring signals. At this point a new design and optimization paradigm based on real wires is...

Film music is as old as cinema itself. Years before synchronized sound became the norm, projected moving images were shown to musical accompaniment, whether performed by a lone piano player or a hundred-piece orchestra. Today film music has become its own industry, indispensable to the marketability of movies around the world.
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Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research...

In Pro Drupal as an Enterprise Development Platform authors Jamie Kurtz and Thomas Besluau explain how developers can save themselves time and money, and build their applications faster with fewer bugs by using the Drupal CMS as a foundation for their projects. The days when custom client applications were built entirely from scratch...

A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated...

This book demonstrates how representations of the Victorian suburb in mid- to late-nineteenth century British writing occasioned a literary sub-genre unique to this period, one that attempted to reassure readers that the suburb was a place where outsiders could be controlled and where middle-class values could be enforced. Whelan explores the...