This book explores the challenges and presents best strategies for designing Through-Silicon Vias (TSVs) for 3D integrated circuits. It describes a novel technique to mitigate TSV-induced noise, the GND Plug, which is superior to others adapted from 2-D planar technologies, such as a backside ground plane and traditional substrate contacts....

This book exposes a number of mathematical models for fracture of growing difficulty. All models are treated in a unified way, based on incremental energy minimization. They differ from each other by the assumptions made on the inelastic part of the total energy, here called the "cohesive energy". Each model describes a specific...

The book introduces ‘the state of the art' of pulsed laser ablation and its applications. It is based on recent theoretical and experimental studies. The book reaches from the basics to advanced topics of pulsed laser ablation. Theoretical and experimental fundamental phenomena involved in pulsed laser ablation are discussed with...

The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful...

A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by...

This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and...

One of the most significant areas of advance in clinical medicine over the last 20 years has been in the imaging technologies. It is difficult to point to the single method or application that has benefited most from those advances because nearly all specialities in medicine have been involved. Perhaps the most significant trend, however, has...

Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an...

This text provides an introduction to the science that governs the interaction of light and matter (in the gas phase). It provides readers with the basic knowledge to exploit the light-matter interaction to develop quantitative tools for gas analysis (i.e. optical diagnostics) and understand and interpret the results of spectroscopic...

The book first presents a detailed discussion of the roots of Ramsey theory before offering a thorough discussion of the...

The book highlights and analyses the distress to buildings caused by sulphate-induced heave, with particular reference to the recent problems in the Dublin area of Ireland. It describes the formation of pyrite, the processes involved in its oxidation and the various ways in which consequential expansion takes place. For the first time in the...