Many bacterial ADP-ribosyltransferases are potent bacterial protein toxins and important
virulence factors. After cellular uptake caused by highly efficient cell entry mechanisms,
they modify eukaryotic target proteins with great specificity and often grossly affect biological
functions of their targets. These properties of the...
The latest research regarding the neurodegenerative conditions known as neuroacanthocytosis will be found in this book. Recent advances have identified the range of mutations in the causative genes. In vitro studies have identified potential protein interactions, and work on erythrocyte membranes suggests mechanisms for the generation of...
This book provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulate the hosts’ immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step-wise fashion take the reader through the fascinating sequence of...
This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book...
This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular...
Computational Intelligence (CI) has been a tremendously active area of - search for the past decade or so. There are many successful applications of CI in many sub elds of biology, including bioinformatics, computational - nomics, protein structure prediction, or neuronal systems modeling and an- ysis. However, there still are many open...
A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity, Volume 1: In Vitro Assays provides a panel of 16 in vitro measures of chemosensitivity in adherent and...
Increased public awareness of the importance of healthy living presents new challenges for the commercial food processing sector. The industry is always on the hunt for novel and safe additives with functional properties that can be used to impart healthy and appealing properties to foods. While the ocean is known as a conventional source of...
The common beans and pulses are diverse food resources of high nutritional value (protein, energy, fiber and vitamins and minerals) with broad social acceptance. These legume crops demonstrate global adaptability, genotypic and phenotypic diversity, and multiple means of preparation and dietary use. Beans and pulses are produced in...
Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.
The Molecular Genetics of Lung Cancer describes how the new...
This volume provides up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to...
There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders. The volume is relevant to a wide readership including cell biologists interested in understanding how structural and...
