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 The p53 Tumor Suppressor Pathway and Cancer (Protein Reviews, Vol. 2)
The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. The emerging ?eld ?rst considered p53 as a viral antigen and then as an oncogene that cooperates with activated ras in transforming primary cells in culture. Fueling the concept of p53 acting as a transforming factor, p53 expression was markedly... |  |  Genomics, Proteomics and Vaccines
While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful... |  |  Cellular Proteins and Their Fatty Acids in Health and Disease
In light of the increasing importance of these proteins and their ligands for our understanding of cellular growth, differentiation, and development, as well as of diseases such as obesity, insulin resistance, atherosclerosis, cancer, and inflammation, a team of internationally renowned editors and authors have compiled here the very first... |
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 Computer Models in Biomechanics: From Nano to Macro
This book contains a collection of papers that were presented at the IUTAM Symposium
on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011.
It contains state-of-the-art papers on:
- Protein and Cell... |  |  |  |  Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine
Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of... |
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