A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the...

Endocrine Replacement Therapy in Clinical Practice, an update of Hormone Repla- ment Therapy published by Humana Press in 1999, aims to assist the endocrinologist, gynecologist, pediatrician, urologist, general surgeon, neurologist, neurosurgeon, p- chiatrist, generalist, and trainee in management of their patients with hormonal defici- cies...

Henry Frederick Baker (1866-1956) was a renowned British mathematician specialising in algebraic geometry. He was elected a Fellow of the Royal Society in 1898 and appointed the Lowndean Professor of Astronomy and Geometry in the University of Cambridge in 1914. First published between 1922 and 1925, the six-volume Principles of Geometry was...

The topics of control engineering and signal processing continue to flourish and develop. In common with general scientific investigation, new ideas, concepts and interpretations emerge quite spontaneously and these are then discussed, used, discarded or subsumed into the prevailing subject paradigm. Sometimes these innovative concepts...

This book...

​This book undertakes to marry the concepts of "Concept Mapping" with a "Design Thinking" approach in the context of business analysis. While in the past a lot of attention has been paid to the business process side, this book now focusses information quality and valuation, master data and hierarchy management,...

The focus of the book, Development of Aneurysms, is a detailed discussion of the biology of aneurysms. Aneurysm formation is influenced by alterations in arterial wall protein synthesis, hemodynamic forces, arterial wall inflammation, and matrix protein degradation. The relationships of these forces provide a unified theory for the...

Polyoxymethylene Handbook: Structure, Properties, Applications, and Their Nanocomposites summarizes many of the...

Scalable Big Data Architecture covers real-world,...

Information granules, as encountered in natural language, are implicit in nature. To make them fully operational so they can be effectively used to analyze and design intelligent systems, information granules need to be made explicit. An emerging discipline, granular computing focuses on formalizing information granules and unifying them to...

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the...

A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated...