When the U.S. liberated the Philippines from Spanish rule in 1898, the exploit was hailed at home as a great moral victory, an instance of Uncle Sam freeing an oppressed country from colonial tyranny. The next move, however, was hotly contested: should the U.S. annex the archipelago? The disputants did agree on one point: that the United...

With fingers blistered and eyes bloodshot, all your hard work is about to pay off. After one hundred hours of playing the newest computer-based roleplaying game, you’ve managed to reach the end. All that stands between you and victory is a very large, very angry dragon. Not to worry though—you have a couple of tricks up your...

From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive...

Their passionate encounter happened long ago by whatever measurement Claire Randall took. Two decades before, she had traveled back in time and into the arms of a gallant eighteenth-century Scot named...