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 |  |  Immunodominance
The normal, intact immune system does not have equal probability of responding
to every potential part of a protein. It has been known for more than 50 years that
only parts of the protein that are “outside” are available for antibody binding. Yet,
with the advent of Western blotting techniques, antibodies that react... |  |  Clear Leadership: Sustaining Real Collaboration and Partnership at Work
All over the world we are witnessing a revolution in organizing. Just as the
industrial revolution created its new form of organization (bureaucracy),
the information revolution is creating its own new form of organization.
We are moving from command and control to collaboration, from organizing
based on a few leaders telling... |
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 |  |  Cytokines and Chemokines in Infectious Diseases Handbook (Infectious Disease)
Cytokines and chemokines are an important class of effector molecules that play a fundamental
role in orchestrating the innate and acquired immune responses needed to eliminate or
wall off invading pathogens. In vitro and in vivo studies have been instrumental in revealing
the complexity of the cytokine network and the many facets of... |  |  |
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