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Immunodominance
Immunodominance
The normal, intact immune system does not have equal probability of responding to every potential part of a protein. It has been known for more than 50 years that only parts of the protein that are “outside” are available for antibody binding. Yet, with the advent of Western blotting techniques, antibodies that react...
Prevention and Treatment of Age-related Diseases
Prevention and Treatment of Age-related Diseases
During the last 40 years, biogerontology – the study of the biological basis of aging – has progressed tremendously, and it has now become an independent and respectable field of study and research. Numerous universities, medical institutes and research centers throughout the world now offer full-fledged courses on the...
Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications
Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications

In the post-genomic era we have, at our fingertips, an incredible array of genomic sequences from a multitude of complex organisms. There remains, however, the critical need to understand the precise roles individual genes play in complex biological milieu. Synthetic nucleic acids are at the cutting-edge of molecular strategies that target...

Mastering Scientific and Medical Writing: A Self-help Guide
Mastering Scientific and Medical Writing: A Self-help Guide
You may ask why anyone would want to write yet another book about scientific writing. There are many books on the subject, some more useful than others, and the abundance of literature on this topic may confuse rather than guide.

I felt that this book was necessary for several reasons. During the past years, I
...
Diseases of the Liver & Biliary System
Diseases of the Liver & Biliary System
The eleventh edition welcomes the new Millenium. Progress in basic and clinical hepatology remains exponential. Since 1997, the advances have been wideranging, with those in molecular and cellular biology, and in diagnosis and treatment, leading the way. In a world in which information technology gives all too ready...
Operations Excellence: Smart Solutions for Business Success (International Management Knowledge)
Operations Excellence: Smart Solutions for Business Success (International Management Knowledge)
Achieving operative excellence is an important endeavor for all companies – it is the golden path that leads to increased value over the long term.

By applying operative levers systematically and managing them correctly, companies are doing everything in their power to ensure that
...
Radiation Oncology Advances (Cancer Treatment and Research)
Radiation Oncology Advances (Cancer Treatment and Research)

Radiation therapy remains a mainstay of cancer treatment: it is estimated that around half of all cancer patients in Europe, in the US probably close to two-thirds, receive radiation therapy as part of their initial therapy, for salvage or for palliation. There are good reasons to expect the role of radiation therapy in the management of...

Signal Processing, Perceptual Coding and Watermarking of Digital Audio: Advanced Technologies and Models (Premier Reference Source)
Signal Processing, Perceptual Coding and Watermarking of Digital Audio: Advanced Technologies and Models (Premier Reference Source)
The availability of increased computational power and the proliferation of the Internet have facilitated the production and distribution of unauthorized copies of multimedia information. As a result, the problem of copyright protection has attracted the interest of the worldwide scientific and business communities. The most...
Computational Cardiology: Modeling of Anatomy, Electrophysiology, and Mechanics (Lecture Notes in Computer Science)
Computational Cardiology: Modeling of Anatomy, Electrophysiology, and Mechanics (Lecture Notes in Computer Science)
Biomedical research is at a critical point at present. The research has led to an enormous amount of data and models describing these data, but approaches for application, formalization and integration of this knowledge from the molecular to the system level are still topics of ongoing research and certainly far from fully...
Deciding Who Leads: How Executive Recruiters Drive, Direct, and Disrupt the Global Search for Leadership Talent
Deciding Who Leads: How Executive Recruiters Drive, Direct, and Disrupt the Global Search for Leadership Talent
Leadership recruiting and succession rank as the most pivotal agendas for today’s growth-minded, change-oriented organizations. Given the risks and rewards inherent in senior-management recruiting, deciding who leads is the quintessential challenge faced by boards of directors, senior corporate officers, and division or...
Essential Physical Medicine and Rehabilitation (Musculoskeletal Medicine)
Essential Physical Medicine and Rehabilitation (Musculoskeletal Medicine)
When I was a medical student interested in physical medicine and rehabilitation (PM&R), I found several excellent detailed texts for PM&R and I also encountered a few good, quick reference materials. What I felt was lacking was a comprehensive but high-yield, focused review of the most important points that I could read...
Analyzing Computer Security: A Threat / Vulnerability / Countermeasure Approach
Analyzing Computer Security: A Threat / Vulnerability / Countermeasure Approach

“In this book, the authors adopt a refreshingly new approach to explaining the intricacies of the security and privacy challenge that is particularly well suited to today’s cybersecurity challenges. Their use of the threat–vulnerability–countermeasure paradigm combined with...

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