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DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development)
DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development)
The field of DNA repair has been the subject of increasing interest at both the genetic and biochemical levels, leading to impressive progress in this area. DNA repair and its associated regulatory mechanisms lie at the heart of almost every fundamental aspect of cell biology, including transcription, cell cycle, apoptosis, and...
Sertoli Cell Biology (Vol 1)
Sertoli Cell Biology (Vol 1)
In 1993 Lonnie Russell and Michael Griswold edited a book titled The Sertoli Cell, which has served as a major resource for investigators interested in male reproduction. It is appropriate that now—more than 10 years later—the advances in this field are summarized in this new text. It is also appropriate that...
Immunodominance
Immunodominance
The normal, intact immune system does not have equal probability of responding to every potential part of a protein. It has been known for more than 50 years that only parts of the protein that are “outside” are available for antibody binding. Yet, with the advent of Western blotting techniques, antibodies that react...
Pediatric Allergy, Asthma and Immunology
Pediatric Allergy, Asthma and Immunology
Pediatric Allergy,Asthma and Immunology is a new discipline that finds its foundation in this book, whose roots linke me to Elena and Luisa Businco,with whom I founded the first Italian Pediatric Allergy Division some 30years ago, now called the Pediatric Allergy and Immunology Division. There I discovered this world,...
BioMEMS and Biomedical Nanotechnology
BioMEMS and Biomedical Nanotechnology
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving theway many important genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a...
Microarrays in Clinical Diagnostics (Methods in Molecular Medicine)
Microarrays in Clinical Diagnostics (Methods in Molecular Medicine)
Within the last decade, microarray technology has evolved from an emerging technology developed and used by a few laboratories into a well-established technology used in laboratories all over the world. In fact, the need to characterize genetic alterations is one of the highest priorities for the future of medicine and the...
Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications (Methods in Pharmacology and Toxicology)
Over the past three decades the field of immunotoxicology, the study of the effects of exposure to drugs, chemicals, or physical/environmental agents on the structure and function of the immune system has benefited from an increasingly detailed understanding of the cellular and molecular basis of innate and acquired immunity....
Macrophages: A Practical Approach
Macrophages: A Practical Approach

Macrophages are an important part of the immune response and are characterized by their ability to phagocytose foreign matter. However the difficulties involved in macrophage isolation mean they are some of the body's least explored cells. Macrophage Methodology describes how to isolate moderate to high yields of viable cells...

Personal Development for Smart People: The Conscious Pursuit of Personal Growth
Personal Development for Smart People: The Conscious Pursuit of Personal Growth

Despite promises of “fast and easy” results from slick marketers, real personal growth is neither fast nor easy. The truth is that hard work, courage, and self-discipline are required to achieve meaningful results—results that are not attained by those who cling to the fantasy of achievement without effort.

Resveratrol in Health and Disease (Oxidative Stress and Disease)
Resveratrol in Health and Disease (Oxidative Stress and Disease)

Practicing evidenced-based medicine some 25 centuries ago, Hippocrates proclaimed "Let food be thy medicine and medicine be thy food." This advice parallels the common American saying, "You are what you eat," and is supported by a National Institute of Health recommendation to consume as many as eight servings of fruits...

Neurobiology of Aggression and Rage
Neurobiology of Aggression and Rage

While other books concentrate on the different facets of aggression, these publications tend to focus on a single aspect of the subject and do not make any attempt to integrate biology and behavior. This lack of integration in the literature has created a major gap in our current understanding of the factors that influence aggressive...

Proteases and Their Inhibitors in Cancer Metastasis (Cancer Metastasis - Biology and Treatment)
Proteases and Their Inhibitors in Cancer Metastasis (Cancer Metastasis - Biology and Treatment)

In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor...

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