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Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)
Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)

12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are,...

Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)
Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology)

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this...

Peripheral Arterial Disease: Diagnosis and Treatment (Contemporary Cardiology)
Peripheral Arterial Disease: Diagnosis and Treatment (Contemporary Cardiology)

Recognized experts comprehensively review the clinical, surgical, radiological, and scientific aspects of atherosclerotic peripheral arterial disease (PAD), including endovascular, gene, and drug therapies. In their far-ranging discussions, the authors examine in depth the risk factors and antiplatelet therapies for PAD patients at high risk...

53: Scientific Foundations of Clinical Practice: Part II, An Issue of Pediatric Clinics, 1e (The Clinics: Internal Medicine)
53: Scientific Foundations of Clinical Practice: Part II, An Issue of Pediatric Clinics, 1e (The Clinics: Internal Medicine)

In the last decade, the delineation of the human genome and the development of high throughput genomics and proteomics have transformed the practice of Pediatrics. The study of normal childhood growth and development, and pediatric diseases now focuses on the delineation of normal and abnormal gene expression, resultant cellular and organ...

53: Scientific Foundations of Clinical Practice: Part I, An Issue of Pediatric Clinics, 1e (The Clinics: Internal Medicine)
53: Scientific Foundations of Clinical Practice: Part I, An Issue of Pediatric Clinics, 1e (The Clinics: Internal Medicine)

In the last decade, the delineation of the human genome and the development of high throughput genomics and proteomics have transformed the practice of Pediatrics. The study of normal childhood growth and development, and pediatric diseases now focuses on the delineation of normal and abnormal gene expression, resultant cellular and organ...

Personalized Nutrition: Principles and Applications
Personalized Nutrition: Principles and Applications

From one person to the next, optimal health is governed by a huge array of minor genetic differences. When modulated by a variety of food bioiactives, these differences result in changes in gene expression and subsequent phenotypic expression. Combining biomedical and social science with contributions from leaders in both fields, Personalized...

The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods (Mycology)
The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods (Mycology)

With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution. The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods provides a comprehensive analysis of the...

Analysis of Growth Factor Signaling in Embryos (Methods in Signal Transduction Series)
Analysis of Growth Factor Signaling in Embryos (Methods in Signal Transduction Series)

Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos.

Focusing on specific pathways...

Tissue Stem Cells
Tissue Stem Cells

Tissue stem cells and their medical applications have become a major focus of research over the past decade. With 16 full-color illustrations, this reference provides a thorough and up-to-date overview of the current and emerging technologies for stem cell research and transplantation. Divided into three sections covering general issues,...

Tourette Syndrome (Advances in Neurology)
Tourette Syndrome (Advances in Neurology)

This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS...

Bioinformatics: Databases and Systems
Bioinformatics: Databases and Systems

Bioinformatics brings computational methods to the analysis and processing of genomic data. Bioinformatics: Databases and Systems focuses on the issues of system building and data curation that dominate the day-to-day concerns of bioinformatics practitioners. Included are chapters by many of today's leading bioinformatics...

Advances in Intelligent Information and Database Systems (Studies in Computational Intelligence)
Advances in Intelligent Information and Database Systems (Studies in Computational Intelligence)

Intelligent information and database systems are two closely related and we- established subfields of modern computer science. They focus on the integration of artificial intelligence and classic database technologies in order to create the class of next generation information systems. The major target of this new gene- tion of systems is to...

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