Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly...

The pharmaceutical industry worldwide is a rapidly burgeoning industry contributing to growth of gross domestic product and employment. Technological change in this field has been very rapid, with many new products being introduced. For this reason in part, health care budgets throughout the world have increased dramatically, eliciting...

The field of multidimensional data structures is large and growing very quickly. Here, for the first time, is a thorough treatment of multidimensional point data, object and image-based representations, intervals and small rectangles, and high-dimensional datasets. The book includes a thorough introduction; a comprehensive survey to spatial...

Cryptography has experienced rapid development, with major advances recently in both secret and public key ciphers, cryptographic hash functions, cryptographic algorithms and multiparty protocols, including their software engineering correctness verification, and various methods of cryptanalysis. This textbook introduces the reader to these...

Human beings are adapted for group living. Groups have a wide range of adaptive functions for individuals, including both material benefits of mutual aid and collective action, and subjective psychological benefits of affiliation and social identity. Recent development of cultural psychology, however, has uncovered that culture plays crucial...

• Transform simple tables into engaging diagrams
• Learn to install Circos on Windows, Linux, and MacOS
• Create Circos diagrams using ribbons, heatmaps, and other data...

The study of surfaces with constant mean curvature (CMC) is one of the main topics in classical differential geometry. Moreover, CMC surfaces are important mathematical models for the physics of interfaces in the absence of gravity, where they separate two different media or for capillary phenomena. Further, as most techniques used in the...

In recent years, cryptographic techniques for protecting and hiding secret information have been included in directions of research on intelligent information management. Data can be managed securely due to the use of algorithms for ensuring the confidentiality of data, information splitting techniques as well as protocols for sharing...

Whether you have years of experience as a teacher or are new to the classroom, you and your students can count on The St. Martin’s Guide to Writing to provide the support you need in first-year composition, with a rhetoric, an array of engaging readings, a research manual, and a handbook, all in a single book...