Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted...

Focusing on specific pathways...

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth...

 “Wireless Networks and Security” provides a broad coverage of wireless security issues including cryptographic coprocessors, encryption, authentication, key management, attacks and countermeasures, secure routing, secure medium access control, intrusion detection, epidemics, security performance analysis, security issues in...

This is a modern textbook on digital communications and is designed for senior undergraduate and graduate students, whilst also providing a valuable reference for those working in the telecommunications industry.  It provides a simple and thorough access to a wide range of topics through use of figures, tables, examples and problem...

Beginning with the description of operating system in general the book discusses features that made Unix the most suitable operating system of its time. An overview of file management in Unix and commonly used Unix commands is then provided. Further, it delves into the detailed description of file system and compression techniques, processes...

Bayesian inference provides a simple and unified approach to data analysis, allowing experimenters to assign probabilities to competing hypotheses of interest, on the basis of the current state of knowledge. By incorporating relevant prior information, it can sometimes improve model parameter estimates by many orders of magnitude. This book...

In three parts, this book contributes to the advancement of engineering education and that serves as a general reference on digital signal processing. Part I presents the basics of analog and digital signals and systems in the time and frequency domain. It covers the core topics: convolution, transforms, filters, and random signal analysis....