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Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases (Advances in Experimental Medicine and Biology)
Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases (Advances in Experimental Medicine and Biology)
This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, October 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the...
COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)
COX-2 Blockade in Cancer Prevention and Therapy (Cancer Drug Discovery and Development)

The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...

Genetics in Ophthalmology (Developments in Ophthalmology) (v. 37)
Genetics in Ophthalmology (Developments in Ophthalmology) (v. 37)

The objective of this publication is to enhance mutual understanding and communication between ophthalmologists, molecular geneticists, genetic counselors and biomedical researchers. In the introductory chapter, current genetic paradigms and experimental genetic approaches relevant to the nature of hereditary disorders are discussed. The...

Brain, Mind and Medicine: Essays in Eighteenth-Century Neuroscience
Brain, Mind and Medicine: Essays in Eighteenth-Century Neuroscience
The idea for a volume on eighteenth-century studies of brain and behavior originated during a joint International Society for the History of the Neurosciences (ISHN) and Theoretical and Experimental Neuropsychology/Neuropsychologie Expérimentale et Théorique (TENNET) symposium held in Montreal in June...
Endocannabinoids: The Brain and Body's Marijuana and Beyond
Endocannabinoids: The Brain and Body's Marijuana and Beyond

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana,  and the finding of endogenous cannabinoids, which...

Deciphering Growth (Research and Perspectives in Endocrine Interactions)
Deciphering Growth (Research and Perspectives in Endocrine Interactions)
An organism’s body size tells us a lot about how it makes a living, suggesting that body size is a key parameter in evolution. We outline three large-scale trends in body size evolution. Bergmann’s Rule is the tendency for warm-blooded species at high latitudes to be larger than their close relatives nearer the equator....
Integrative Physiology in the Proteomics and Post-Genomics Age
Integrative Physiology in the Proteomics and Post-Genomics Age
There is a perception in the scientific community that the discipline of Physiology is in crisis, or at least, in a phase of profound transition and change. At the root of the problem is confusion between objectives (the biological questions to be solved) and the methods and technologies to be applied. Traditionally, ever since...
Seasonal Patterns of Stress, Immune Function, and Disease
Seasonal Patterns of Stress, Immune Function, and Disease
Most animals exhibit seasonal variation in their reproduction and survival simply because most of them live in environments in which food availability varies seasonally. This is true in the tropics as well as at the higher latitudes, but at the higher latitudes the combined challenge of food shortage and low temperature makes...
Introduction to the Cellular and Molecular Biology of Cancer
Introduction to the Cellular and Molecular Biology of Cancer

This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of...

Cardiac Repolarization (Contemporary Cardiology)
Cardiac Repolarization (Contemporary Cardiology)
There are a number of excellent books on molecular biology, single-channel electrophysiology, animal experimentation, and clinical electrophysiology. However, the past decade has seen an explosion of knowledge and radical changes in our understanding of ventricular repolarization as an integral part of the cardiac electrophysiologic...
Orthopoxviruses Pathogenic for Humans
Orthopoxviruses Pathogenic for Humans
The viruses belonging to the genus Orthopoxvirus of the family Poxviridae are among the pathogens heading the list of microorganisms that have had an important role in the interactions between the humankind and infectious agents. Until recently, smallpox, caused by variola virus, was the most dangerous epidemic disease of humans,...
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals

This is a comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The book consists of a general part dealing with themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. The second part includes the...

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