Kernel smoothing refers to a general methodology for recovery of underlying structure in data sets. The basic principle is that local averaging or smoothing is performed with respect to a kernel function.

This book provides uninitiated readers with a feeling for the principles, applications, and analysis of kernel smoothers....

This is the first part in a two-volume work on neuromodulation. It describes techniques and procedures applied in internal contact with non-neural tissues surrounding the nervous system (dura or cerebrospinal fluid), as in the case of epidural stimulation for pain or intrathecal drug application for the treatment of spasticity and pain. In...

This book focuses on the theoretical problems associated with molecular diversity as it is being applied in the pharmaceutical industry. Therefore, this book deals with algorithms that are involved in understanding chemical space and selection of diverse sets of structures. The algorithms also deal with the problem of focused diversity where...

The revelation that aspirin and aspirin-like compounds have notable antineoplastic properties has revolutionized cancer research. COX-2 Blockade in Cancer Prevention and Therapy chronicles the evidence and presents exciting new opportunities for the use of cyclooxygenase-2 (COX-2) blockade in the prevention and treatment of cancer. The text...

What is superconductivity? How was it discovered? What are the properties of superconductors, how are they applied now, and how are they likely to become widely used in the near future? These are just some of the questions which this important book sets out to answer. Starting with the discovery of superconductivity over ninety years ago, the...

Straightforward, systematic approach for designing reliable dc power systems for telecommunications

Here is a must-have resource for anyone responsible for designing, installing, and maintaining telecommunications systems. The text explains how to design direct current (dc) power systems that operate at nominal voltages of 24...

"This is not a book about charismatic visionary leaders. It is not about visionary product concepts or visionary products or visionary market insights. Nor even is it about just having a corporate vision. This is a book about something far more important, enduring, and substantial. This is a book about visionary...

Leading clinicians and researchers critically survey a decade of clinical, biological, and pathological knowledge, and show how it is best applied to the management of both localized and advanced renal cell carcinoma. Their discussions include the latest developments in molecular genetics and immune dysfunction, and fully treat the roles of...

This book provides a hands-on practical guide to using the most suitable models for analysis of statistical data sets using EViews - an interactive Windows-based computer software program for sophisticated data analysis, regression, and...