An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain...
Seeking ways to improve their appearance with little or no "down time," more and more patients are turning to their physicians for the newest, non-invasive technologies.
Here is your complete guide to the most effective, popular, and safe minimally invasive, surgical, and peri-oral rejuvenation techniques. It provides key...
I opened my series editor manuscript of The Handbook of Contraception: A Guide for Practical Management, edited by Drs. Donna Shoupe and Siri Kjos, on a tiny plane on the way to giving a lecture in Albany, NY. I expected to peruse the ma- script, and found that I could not put it down. The Handbook of Contraception: A Guide for Practical...
Many engineering, operations, and scientific applications include a mixture of discrete and continuous decision variables and nonlinear relationships involving the decision variables that have a pronounced effect on the set of feasible and optimal solutions. Mixed-integer nonlinear programming (MINLP) problems combine the numerical...
Food Safety Management: A Practical Guide for the Food Industry with an Honorable Mention for Single Volume Reference/Science in the 2015 PROSE Awards from the Association of American Publishers is the first book to present an integrated, practical approach to the management of food safety throughout the production chain. While many...
A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors.
Materials are the stuff of design. From the very beginning of human history, materials have been taken from the natural world and shaped, modified, and adapted for everything from primitive tools to modern electronics. This renowned book by noted materials engineering author Mike Ashby and industrial designer Kara Johnson explores the role of...
This book covers the latest bio-inspired materials synthesis techniques and biomedical applications that are advancing the field of tissue engineering. Bio-inspired concepts for biomedical engineering are at the forefront of tissue engineering and regenerative medicine. Scientists, engineers and physicians are working together to...
A comprehensive overview of nonlinear H∞ control theory for both continuous-time and discrete-time systems, Nonlinear H∞-Control, Hamiltonian Systems and Hamilton-Jacobi Equations covers topics as diverse as singular nonlinear H∞-control, nonlinear...
Neither pest management nor resistance management can occur with only an understanding of pest biology. For years, entomologists have understood, with their use of economic thresholds, that at least a minimal use of economics was necessary for proper integrated pest management. IRM is even more complicated and dependent on understanding and...
Identification of a physical system deals with the problem of identifying its mathematical model using the measured input and output data. As the physical system is generally complex, nonlinear, and its input–output data is corrupted noise, there are fundamental theoretical and practical issues that need to be...
Oxygen-ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classic biochemical, physiological and pharmacological...