Progress in biology is dependent on the ability to observe, measure, and model the behavior of organisms at multiple levels of abstraction, from the microscopic to the macroscopic. There has been a tremendous growth recently in the techniques to probe the structure and workings of cellular and organ-level mechanisms. Significant advances have...

Diseases of the pancreas have been extremely difficult to study. Until relatively recently, the pancreas was viewed by surgeons as an organ to be avoided, given its deep retroperitoneal location and the sometimes severe consequences of manipulation. Similar difficulties have plagued careful study of the pancreas. In humans, only inf- quently...

Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing...

Human activity, such as burning fossil fuels, is causing a build-up of greenhouse gases such as carbon dioxide (CO2) in the...

Many colleges and universities offer a course in discrete mathematics. Students taking these courses are from many disciplines, one of the largest being computer science. As a part of the Mathematics Across the Curriculum project at Dartmouth, supported by the National Science Foundation,1 we proposed to create a discrete mathematics...

This book is meant for research scholars, scientists and practitioners involved with the application of computer-based systems in critical applications. Ensuring dependability of systems used in critical applications is important due to the impact of their failures on human life, investment and environment. The individual aspects of...

Nanobioelectrochemistry covers the modern aspects of bioelectrochemistry, nanoscience and materials science. The combination of nanostructured materials and biological molecules enables the development of biodevices capable to detect specific substances. Furthermore, by using the bioelectrochemistry approach, the interaction between...

Scientists and academics have spent entire careers investigating what makes people happy. But hidden in obscure scholarly journals and reports, their research is all too often inaccessible to ordinary people. Now the bestselling author of the 100 Simple Secrets series distills the scientific findings of over a thousand of the most important...

This thesis is concerned with the design of efficient algorithms for listing combinatorial structures. The research described here gives some answers to the following questions: which families of combinatorial structures have fast computer algorithms for listing their members, What general methods are useful for listing combinatorial...