The Rough Guide to Tokyo is the ultimate insiders guide to accessing Japan''s dazzling capital, with comprehensive coverage of all the sights, from beautiful traditional gardens to start-of-the-art museums and the iconic new Tokyo Midtown development. It tracks down the latest and best places to sleep, eat, drink and shop and gives...

Circadian rhythms are such an innate part of our lives that we rarely pause to speculate why they even exist. Some studies have suggested that the disruption of the circadian system may be causal for obesity and manifestations of Metabolic Syndrome (MetS). Shift-work, sleep-deprivation and bright-light-exposure at night are related to...

Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus...