Highly experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 1: Nonviral Gene Transfer Techniques focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection,...
We've all sneaked the odd five minutes here or there playing the latest Flash game that someone sent round the office, but creating those games is trickier than it looks. The aim of Foundation Game Design with Flash is to take you, even if you've minimal multimedia or programming experience, through a series of step-by-step examples and detailed...
Presents the latest research and applications for a new, promising approach to fighting infectious diseases
Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book...
Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new...
Apple has been issuing checks to developers, and the 2012 figures indicate that it has so far been
to the tune of $5 billion. In the past, it used to be desktops with Microsoft-based products that were
raking in money for developers, with Visual Basic, or earlier with database products such as dBase
and FoxPro. While the major share...
This book presents a practical approach to the differential diagnosis of pulmonary infections based on their radiographic and CT appearances. The authors discuss the value and limitations of chest radiography, the indications for CT, the optimal CT techniques, and the role of intravenous contrast. Chapters describe and illustrate the...
IT professionals and IT students will find this a handy reference to help them identify terms used in practice, in journals and articles, and on websites. The dictionary has complete coverage of security terms and includes cutting-edge technologies and newer terminology only now becoming accepted use amongst security practitioners. Certification...
This book is a comprehensive guide to how organizations can use the internet to support their marketing activities and covers all aspects of Internet marketing - environment analysis, strategy development and implementation. Building on the successful and widely regarded first edition, this second edition has a completely revised structure and...
Promising drug discovery efforts in the race to cure emerging diseases and thwart bioterrorism
It was not too long ago that scientists believed that the discovery of powerful antimicrobial agents and vaccines would lead to the eradication of viral diseases. A warning, however, of the looming threat of viral diseases on U.S. national security...
Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory...
Since the pioneering discovery by Felgner et al. (1987) that cationic lipid
can efficiently transfect cells, there was a surge of research activity in this
area. The field received another boost when Nabel et al. (1993) successfully
completed a small phase I clinical trial in gene therapy of melanoma
using cationic liposome as a...