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Prefrontal Cortex: From Synaptic Plasticity to Cognition
Prefrontal Cortex: From Synaptic Plasticity to Cognition

This volume, Prefrontal Cortex: from Synaptic Plasticity to Cognition, is an interdisciplinary approach to characterize the function of the anterior portion of the frontal lobe in rodents and human and non-human primates. The specific topics discussed in the chapters of this volume are purposefully diverse: they range from membrane properties...

The Complement System: Novel Roles in Health and Disease
The Complement System: Novel Roles in Health and Disease

As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost...

Molecular Basis of Thyroid Cancer (Cancer Treatment and Research)
Molecular Basis of Thyroid Cancer (Cancer Treatment and Research)
Thyroid cancer is the fastest growing cancer in the U.S., especially among women. Given the relative success we have had in its treatment, there is a need to capitalize on it by better understanding the factors that underpin this malignancy, and exploring better strategies for diagnosis, treatment, and follow-up. To do so, we must...
Brain Damage and Repair: From Molecular Research to Clinical Therapy
Brain Damage and Repair: From Molecular Research to Clinical Therapy

This book builds a novel bridge from molecular research to clinical therapy. This approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes...

Structure-based Drug Discovery
Structure-based Drug Discovery

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as...

New Insights in Medical Mycology
New Insights in Medical Mycology

The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host’s immune response. Each chapter focuses on a specific fungal pathogen or group of pathogens, and examines their biology and the factors that allow the fungus to colonize and...

Halophilic Microorganisms and their Environments (Cellular Origin, Life in Extreme Habitats and Astrobiology)
Halophilic Microorganisms and their Environments (Cellular Origin, Life in Extreme Habitats and Astrobiology)

"This water" he told me, "runs out to the eastern region, and flows into the Arabah; and when it comes into the sea, into the sea of foul waters [i. e. , the Dead Sea], the water will become wholesome. Every living creature that swarms will be able to live wherever this stream goes; the fish will be very abundant once these...

Risk Assessment of Chemicals: An Introduction
Risk Assessment of Chemicals: An Introduction

At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources,...

Mechanics of Composite Materials with MATLAB
Mechanics of Composite Materials with MATLAB

This is a book for people who love mechanics of composite materials and ? MATLAB . We will use the popular computer package MATLAB as a matrix calculator for doing the numerical calculations needed in mechanics of c- posite materials. In particular, the steps of the mechanical calculations will be emphasized in this book. The reader will not...

SOI Design: Analog, Memory and Digital Techniques
SOI Design: Analog, Memory and Digital Techniques

This title introduces state-of-the-art design principles for SOI circuit design, and is primarily concerned with circuit-related issues. It considers SOI material in terms of implementation that is promising or has been used elsewhere in circuit development, with historical perspective where appropriate.

In the 1850’s my
...
Frontiers of Statistical Decision Making and Bayesian Analysis: In Honor of James O. Berger
Frontiers of Statistical Decision Making and Bayesian Analysis: In Honor of James O. Berger

Research in Bayesian analysis and statistical decision theory is rapidly expanding and diversifying, making it increasingly more difficult for any single researcher to stay up to date on all current research frontiers. This book provides a review of current research challenges and opportunities. While the book can not exhaustively cover all...

Mixed Integer Nonlinear Programming (The IMA Volumes in Mathematics and its Applications)
Mixed Integer Nonlinear Programming (The IMA Volumes in Mathematics and its Applications)

Many engineering, operations, and scientific applications include a mixture of discrete and continuous decision variables and nonlinear relationships involving the decision variables that have a pronounced effect on the set of feasible and optimal solutions. Mixed-integer nonlinear programming (MINLP) problems combine the numerical...

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