Despite rapidly expanding interest in potential applications of surrogate tissue analysis and intense competition to identify and validate biomarkers in appropriate surrogate tissues, very few peer reviewed publications describing the use of this approach have appeared in the scientific press. One of the first publications on this topic,...

With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution. The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods provides a comprehensive analysis of the...

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species...

Oral health is an intrinsic part of overall health. The mouth is part of the digestive and respiratory systems; it is essential to spoken communication and facial expression; in fact, toothaches are among the most severe and hence debilitating kinds of pain that a person can suffer. The economic cost of dental disease is staggering, equaling...

Many hiphoppas labour to sustain Hiphop Kulture in their communities far from the big stages, world tours, and hit singles enjoyed by a shockingly few American hiphoppas. The creative labour of these few mega stars is calculated in billions of dollars. But for most hiphoppas, their creative labour may never get expressed in economic terms....

This book investigates the growing and ever-changing health issues for girls and women who lead an active lifestyle and participate in sports and exercise. Easy to read, the volume provides an educational foundation for understanding how disordered eating, amenorrhea, and osteoporosis can be interrelated while also looking at image disorders...

• Includes a chronology of key decisions, cases, and government action in the development...

Parallel trade in pharmaceuticals within the EU involves the legal repacking and reselling of genuine medicines and dates back to the 1970s when a number of pharmacists realized that drug prices varied significantly between member states. By 2002, the UK market for parallel-distributed pharmaceuticals represented £1,300 million. It is...

Leading oncologists, hematologists, and nephrologists comprehensively review the role of HGFs in clinical practice, explain the molecular basis of their effects, and consider potential future developments. The authors focus on the use of HGFs in oncology, describing their cutting-edge application to patients with lung cancer, Hodgkin's...

This Orthopedic Clinics of North America addresses important practice management guidelines necessary to survive and thrive in today's marketplace. Unfortunately, due to continued reductions in Medicare and private payor reimbursements, it is more important than ever to understand the "business" aspects of orthopedics and...