One of the most fruitful areas of research, as judged by the very large numbers of new cancer genes identified, has been the molecular analysis of recurrent chromosomal translocations. The original concept that gave rise to this book was that key scientists involved in the original isolation of the genes involved in each recurrent solid tumor...

This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future...

Considerable evidence indicates that the U.S. is falling behind when it comes to innovation. In part, this shift stems from the globalization of research and the advancement of other nations. But, it also arises from a widespread failure to adapt to the competitive environment generated by the evolution of science and technology.
The...

The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development. This book consists of a compilation of chapters based on presentations at a...

"In a clear, engaging style, Dr. Walters tells the tale of each disease like a detective story. He allows each mystery to unfold as it did in reality, often slowly, through the lives of the plants and animals involved, the first human victims, the government officials who tried to respond, and the scientists who ultimately explained what...

Nearly everyone within a company is involved in selling at one level or another. Yet, the majority of those people are not professional frontline salespeople - they have never received any training in selling or in dealing with customers. As a result, opportunities are missed and, worse, you may even have wrecked the relationship with the...

This topical volume provides an overview of clinically relevant data on anticancer agents. It is not only intended medical doctors working with cancer patients, and for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics. Apart from new targets for...

When Hugh MacLeod was a struggling young copywriter living in a YMCA, he started to doodle on the backs of business cards while sitting at a bar. Those cartoons eventually led to a popular blog-gapingvoid.com-and a reputation for pithy insight and humor, in both words and pictures. MacLeod has opinions on everything from marketing to the...

"A very rich book sprinkled with real-life examples as well as battle-tested advice.”
—Pierre Haren, VP ILOG, IBM

"James does a thorough job of explaining Decision Management Systems as enablers
of a formidable business transformation.”
—Deepak Advani, Vice President,...

Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory...

The book aims at presenting technical and financial features of life insurance, non-life insurance, pension plans. The book has been planned assuming non-actuarial readers as its "natural" target, namely - advanced undergraduate and graduate students in Economics, Business and Finance; - professionals and technicians operating in...