In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of...

This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance...

Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first...

Following on from the successful first edition (March 2012), this book gives a clear explanation of what LTE does and how it works. The content is expressed at a systems level, offering readers the opportunity to grasp the key factors that make LTE the hot topic amongst vendors and operators across the globe. The book assumes no more than a...

This is a modern textbook on digital communications and is designed for senior undergraduate and graduate students, whilst also providing a valuable reference for those working in the telecommunications industry.  It provides a simple and thorough access to a wide range of topics through use of figures, tables, examples and problem...

In three parts, this book contributes to the advancement of engineering education and that serves as a general reference on digital signal processing. Part I presents the basics of analog and digital signals and systems in the time and frequency domain. It covers the core topics: convolution, transforms, filters, and random signal analysis....